Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling

Enhanced anti-tumour effects of Vinca alkaloids given separately from cytostatic therapies

(2012) H Ehrhardt et al.   BRITISH JOURNAL OF PHARMACOLOGY

Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice

(2012) Ines Höfig et al.   Cell Communication and Signaling

Next-Generation cDNA Screening for Oncogene and Resistance Phenotypes

(2012) Nobuaki Shindoh et al.   PLoS One

The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL

(2012) M Grunert et al.   Cell Death & Disease

Optimized anti-tumor effects of anthracyclines plus Vinca alkaloids using a novel, mechanism-based application schedule

(2011) H. Ehrhardt et al.   BLOOD

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

Important Role of Caspase-8 for Chemosensitivity of ALL Cells

(2011) H. Ehrhardt et al.   CLINICAL CANCER RESEARCH

The p53 Pathway as a Target in Cancer Therapeutics: Obstacles and Promise

(2011) A. Mandinova et al.   Science Translational Medicine

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Life or death

(2010) Katharina Schlereth et al.   CELL CYCLE

The role of mutant p53 in human cancer

(2010) Amanda M Goh et al.   JOURNAL OF PATHOLOGY

Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial

(2010) Anthony V Moorman et al.   LANCET ONCOLOGY

DNA Binding Cooperativity of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis

(2010) Katharina Schlereth et al.   MOLECULAR CELL

Translating p53 into the clinic

(2010) Chit Fang Cheok et al.   Nature Reviews Clinical Oncology

New insights into apoptosis signaling by Apo2L/TRAIL

(2010) F Gonzalvez et al.   ONCOGENE

Modulating the p53 pathway

(2010) Anwesha Dey et al.   SEMINARS IN CANCER BIOLOGY

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dark side of a tumor suppressor: anti-apoptotic p53

(2008) R U Jänicke et al.   CELL DEATH AND DIFFERENTIATION