Insights into Desmosome Biology from Inherited Human Skin Disease and Cardiocutaneous Syndromes

Desmosome Assembly and Disassembly Are Membrane Raft-Dependent

(2014) Sara N. Stahley et al.   PLoS One

Mechanistic Basis of Desmosome-Targeted Diseases

(2013) Caezar Al-Jassar et al.   JOURNAL OF MOLECULAR BIOLOGY

Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting

(2013) Liat Samuelov et al.   NATURE GENETICS

Desmosome assembly and dynamics

(2013) Oxana Nekrasova et al.   TRENDS IN CELL BIOLOGY

RHBDF2 Mutations Are Associated with Tylosis, a Familial Esophageal Cancer Syndrome

(2012) Diana C. Blaydon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Involvement of the ubiquitin-proteasome system in the stabilization of cell-cell contacts in human keratinocytes

(2012) Stefanie Löffek et al.   EXPERIMENTAL DERMATOLOGY

Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer

(2012) Silva Saarinen et al.   Familial Cancer

Lack of Plakoglobin in Epidermis Leads to Keratoderma

(2012) Deqiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DSPII splice variant is crucial for desmosome-mediated adhesion in HaCaT keratinocytes

(2012) Rita M. Cabral et al.   JOURNAL OF CELL SCIENCE

SERCA2-Controlled Ca2+-Dependent Keratinocyte Adhesion and Differentiation Is Mediated via the Sphingolipid Pathway: A Therapeutic Target for Darier's Disease

(2012) Anna Celli et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tumor Necrosis Factor Signaling Requires iRhom2 to Promote Trafficking and Activation of TACE

(2012) C. Adrain et al.   SCIENCE

iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against Listeria and Responses to LPS

(2012) D. R. McIlwain et al.   SCIENCE

Mutations in CSTA, Encoding Cystatin A, Underlie Exfoliative Ichthyosis and Reveal a Role for This Protease Inhibitor in Cell-Cell Adhesion

(2011) Diana C. Blaydon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ectodermal dysplasia-skin fragility syndrome due to a new homozygous internal deletion mutation in the PKP1 gene

(2011) Aaron E Boyce et al.   AUSTRALASIAN JOURNAL OF DERMATOLOGY

Cardiomyopathy with alopecia and palmoplantar keratoderma (CAPK) is caused by a JUP mutation

(2011) H. Erken et al.   BRITISH JOURNAL OF DERMATOLOGY

Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity

(2011) Manuela Pigors et al.   HUMAN MOLECULAR GENETICS

Cell-cell connectivity: desmosomes and disease

(2011) Matthew A Brooke et al.   JOURNAL OF PATHOLOGY

Inflammatory Skin and Bowel Disease Linked toADAM17Deletion

(2011) Diana C. Blaydon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and characterization of DSPIa, a novel isoform of human desmoplakin

(2010) Rita M. Cabral et al.   CELL AND TISSUE RESEARCH

The Cardiac Desmosome and Arrhythmogenic Cardiomyopathies

(2010) Mario Delmar et al.   CIRCULATION RESEARCH

The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling

(2010) Ryan P. Hobbs et al.   FASEB JOURNAL

Homozygous Mutations in the 5′ Region of the JUP Gene Result in Cutaneous Disease but Normal Heart Development in Children

(2010) Rita M. Cabral et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Homozygous Nonsense Mutation in the Human Desmocollin-3 (DSC3) Gene Underlies Hereditary Hypotrichosis and Recurrent Skin Vesicles

(2009) Muhammad Ayub et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel truncating mutations inPKP1andDSPcause similar skin phenotypes in two Brazilian families

(2009) A. Tanaka et al.   BRITISH JOURNAL OF DERMATOLOGY

Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell–cell detachment and processing of adhesion molecules via mechanisms that involve PKC

(2009) Nicola Cirillo et al.   EXPERIMENTAL CELL RESEARCH

Interactions of Plakoglobin and β-Catenin with Desmosomal Cadherins

(2009) Hee-Jung Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Desmosomes at a glance

(2009) Bhushan V. Desai et al.   JOURNAL OF CELL SCIENCE

The Desmosome

(2009) E. Delva et al.   Cold Spring Harbor Perspectives in Biology

Intercellular Junction Assembly, Dynamics, and Homeostasis

(2009) K. J. Green et al.   Cold Spring Harbor Perspectives in Biology

Homozygous Mutation of Desmocollin-2 in Arrhythmogenic Right Ventricular Cardiomyopathy with Mild Palmoplantar Keratoderma and Woolly Hair

(2008) M.A. Simpson et al.   CARDIOLOGY

Plakophilin 2: a critical scaffold for PKCα that regulates intercellular junction assembly

(2008) Amanda E. Bass-Zubek et al.   JOURNAL OF CELL BIOLOGY

Plakoglobin Is Required for Effective Intermediate Filament Anchorage to Desmosomes

(2008) Devrim Acehan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

EGFR and ADAMs Cooperate to Regulate Shedding and Endocytic Trafficking of the Desmosomal Cadherin Desmoglein 2

(2008) Jodi L. Klessner et al.   MOLECULAR BIOLOGY OF THE CELL

The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer

(2008) Jessica Pruessmeyer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Plakophilin-3-Deficient Mice Develop Hair Coat Abnormalities and Are Prone to Cutaneous Inflammation

(2007) Tatyana Sklyarova et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY