Nimbolide inhibits IGF-I-mediated PI3K/Akt and MAPK signalling in human breast cancer cell lines (MCF-7 and MDA-MB-231)

Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway

(2012) P. Elumalai et al.   TOXICOLOGY LETTERS

Induction of apoptosis and inhibition of PI3K/Akt pathway in PC-3 and LNCaP prostate cancer cells by ethanolic neem leaf extract

(2011) Dharmalingam N. Gunadharini et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-κB in colon cancer cells

(2011) Suboj Babykutty et al.   MOLECULAR CARCINOGENESIS

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

New avenues to target Wnt/β-catenin signaling

(2010) Folkert Verkaar et al.   DRUG DISCOVERY TODAY

The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells

(2010) R. Vidya Priyadarsini et al.   FREE RADICAL RESEARCH

Nimbolide Sensitizes Human Colon Cancer Cells to TRAIL through Reactive Oxygen Species- and ERK-dependent Up-regulation of Death Receptors, p53, and Bax

(2010) Subash C. Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Chemotherapeutic Agents

(2010) Subash C. Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The neem limonoids azadirachtin and nimbolide inhibit cell proliferation and induce apoptosis in an animal model of oral oncogenesis

(2009) G. Harish Kumar et al.   INVESTIGATIONAL NEW DRUGS

Nimbolide a limonoid from Azadirachta indica inhibits proliferation and induces apoptosis of human choriocarcinoma (BeWo) cells

(2008) G. Harish Kumar et al.   INVESTIGATIONAL NEW DRUGS

The role of herbs and spices in cancer prevention

(2008) Christine M. Kaefer et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Tyrosine Phosphorylation of the Nuclear Receptor Coactivator AIB1/SRC-3 Is Enhanced by Abl Kinase and Is Required for Its Activity in Cancer Cells

(2008) A. S. Oh et al.   MOLECULAR AND CELLULAR BIOLOGY

Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways

(2008) Sonia Ramos   MOLECULAR NUTRITION & FOOD RESEARCH

GSK-3β regulates cyclin D1 expression: A new target for chemotherapy

(2007) Fumi Takahashi-Yanaga et al.   CELLULAR SIGNALLING