Inhibition of autophagy enhances apoptosis induced by the PI3K/AKT/mTor inhibitor NVP-BEZ235 in renal cell carcinoma cells

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones

(2012) Andrea Cavazzoni et al.   CANCER LETTERS

Antiangiogenic therapy for advanced renal cell carcinoma: Management of treatment-related toxicities

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The dual PI3K and mTOR inhibitor NVP-BEZ235 exhibits anti-proliferative activity and overcomes bortezomib resistance in mantle cell lymphoma cells

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Multi-Level Targeting of the Phosphatidylinositol-3-Kinase Pathway in Non-Small Cell Lung Cancer Cells

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NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity

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A proteolytic cleavage assay to monitor autophagy inDictyostelium discoideum

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Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

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Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy

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Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy

(2011) William S. Holland et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy

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Aberrations of a cell adhesion molecule CADM4 in renal clear cell carcinoma

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The efficacy of a novel, dual PI3K/mTOR inhibitor NVP-BEZ235 to enhance chemotherapy and antiangiogenic response in pancreatic cancer

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Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer

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Targeting renal cell carcinoma with NVP-BEZ235, a dual PI3K/mTOR inhibitor, in combination with sorafenib

(2011) Didier Roulin et al.   Molecular Cancer

Vascular Disruption in Combination with mTOR Inhibition in Renal Cell Carcinoma

(2011) L. Ellis et al.   MOLECULAR CANCER THERAPEUTICS

Targeting autophagy during cancer therapy to improve clinical outcomes

(2011) Jean M. Mulcahy Levy et al.   PHARMACOLOGY & THERAPEUTICS

The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Induces Tumor Regression in a Genetically Engineered Mouse Model of PIK3CA Wild-Type Colorectal Cancer

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Targeting mTOR in renal cell carcinoma

(2010) Gary R. Hudes   CANCER

The Efficacy of the Novel Dual PI3-Kinase/mTOR Inhibitor NVP-BEZ235 Compared with Rapamycin in Renal Cell Carcinoma

(2010) D. C. Cho et al.   CLINICAL CANCER RESEARCH

The Applicability of mTOR Inhibition in Solid Tumors

(2009) I.R. Konings et al.   CURRENT CANCER DRUG TARGETS

mTOR in renal cell cancer: modulator of tumor biology and therapeutic target

(2009) Piotr J Wysocki   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Renal cell carcinoma

(2009) Brian I Rini et al.   LANCET

NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas

(2009) T.-J. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Oxidative Stress Induces Parallel Autophagy and Mitochondria Dysfunction in Human Glioma U251 Cells

(2009) Hongyu Zhang et al.   TOXICOLOGICAL SCIENCES

Autophagy in the Pathogenesis of Disease

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