Synergistic Effect of Phenformin in Non-Small Cell Lung Cancer (NSCLC) Ionizing Radiation Treatment

Oncobiguanides: Paracelsus’ law and nonconventional routes for administering diabetobiguanides for cancer treatment

(2015) Javier A. Menendez et al.   Oncotarget

Metformin and Cancer Risk and Mortality: A Systematic Review and Meta-analysis Taking into Account Biases and Confounders

(2014) S. Gandini et al.   Cancer Prevention Research

Molecular Pathways: Preclinical Models and Clinical Trials with Metformin in Breast Cancer

(2014) A. M. Thompson   CLINICAL CANCER RESEARCH

Commonly used diabetes and cardiovascular medications and cancer recurrence and cancer-specific mortality: a review of the literature

(2014) Jennifer W Wu et al.   Expert Opinion On Drug Safety

Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

(2014) A. Janzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK

(2013) Y Storozhuk et al.   BRITISH JOURNAL OF CANCER

LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin

(2013) David B. Shackelford et al.   CANCER CELL

ER stress suppresses DNA double-strand break repair and sensitizes tumor cells to ionizing radiation by stimulating proteasomal degradation of Rad51

(2013) Tohru Yamamori et al.   FEBS LETTERS

Defining Local-Regional Control and Its Importance in Locally Advanced Non-small Cell Lung Carcinoma

(2012) Mitchell Machtay et al.   Journal of Thoracic Oncology

Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells

(2010) Toran Sanli et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

(2008) Xu Huang et al.   BIOCHEMICAL JOURNAL

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

(2008) James A. Dykens et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY