4.3 Article

Analysis of the Relationship Between Ultrasound of Breast Cancer DOT-SDI and the Expression of MVD, VEGF and HIF-1α

Journal

CELL BIOCHEMISTRY AND BIOPHYSICS
Volume 70, Issue 1, Pages 205-208

Publisher

HUMANA PRESS INC
DOI: 10.1007/s12013-014-9883-x

Keywords

Ultrasound; Breast cancer; MVD; VEGF; HIF-1 alpha

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Ultrasonic light scattering tomography system is a new imaging technique for breast function, which associates with diffused optical tomography (DOT) with ultrasonic examination. A recent study found microvessel density (MVD), vascular endothelial growth factor (VEGF) and hypoxia-inducible factor-1 alpha (HIF-1 alpha) play a major role in angiogenesis of breast cancer. This study analyses the relationship between breast cancer ultrasound synthesis diagnostic index (SDI) and the expression of MVD, VEGF and HIF-1 alpha by testing the expression level of the breast cancer gene MVD, VEGF and HIF-1 alpha. In this study, we disclose the relationship between ultrasound of breast cancer DOT-SDI and the expression of MVD, VEGF and HIF-1 alpha.

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