Icariin Protects Against Glucocorticoid-Induced Osteoporosis In Vitro and Prevents Glucocorticoid-Induced Osteocyte Apoptosis In Vivo

The beneficial effect of Icariin on bone is diminished in osteoprotegerin-deficient mice

(2012) Dong Zheng et al.   BONE

Naringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (UMR-106) cells

(2010) Wai-Yin Pang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells

(2010) Sao-Keng Mok et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways

(2010) Yukiko Kitase et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro

(2010) Hui-Ping Ma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osteocyte: the unrecognized side of bone tissue

(2010) G. Y. Rochefort et al.   OSTEOPOROSIS INTERNATIONAL

Icariin inhibits osteoclast differentiation and bone resorption by suppression of MAPKs/NF-κB regulated HIF-1α and PGE2 synthesis

(2010) Tsai-Pei Hsieh et al.   PHYTOMEDICINE

Preventive Effects of Berberine on Glucocorticoid-Induced Osteoporosis in Rats

(2010) Daohua Xu et al.   PLANTA MEDICA

Prostaglandin E2 Induces CYP1B1 Expression via Ligand-Independent Activation of the ERα Pathway in Human Breast Cancer Cells

(2010) Eun H. Han et al.   TOXICOLOGICAL SCIENCES

Genistein aglycone reverses glucocorticoid-induced osteoporosis and increases bone breaking strength in rats: a comparative study with alendronate

(2009) A Bitto et al.   BRITISH JOURNAL OF PHARMACOLOGY

Methoxylated isoflavones, cajanin and isoformononetin, have non-estrogenic bone forming effect via differential mitogen activated protein kinase (MAPK) signaling

(2009) Biju Bhargavan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Antiosteoporotic activity of icariin in ovariectomized rats

(2009) H. Nian et al.   PHYTOMEDICINE

Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells

(2008) Byung-Hee Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Modulation of Dickkopf-1 Attenuates Glucocorticoid Induction of Osteoblast Apoptosis, Adipocytic Differentiation, and Bone Mass Loss

(2008) Feng-Sheng Wang et al.   ENDOCRINOLOGY

Glucocorticoid induces apoptosis of osteoblast cells through the activation of glycogen synthase kinase 3β

(2008) Sun-Il Yun et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Apoptotic Bodies Convey Activity Capable of Initiating Osteoclastogenesis and Localized Bone Destruction

(2008) Giolanta Kogianni et al.   JOURNAL OF BONE AND MINERAL RESEARCH