The Glutamate Aspartate Transporter (GLAST) Mediates l-Glutamate-Stimulated Ascorbate-Release Via Swelling-Activated Anion Channels in Cultured Neonatal Rodent Astrocytes

Ascorbic acid: Chemistry, biology and the treatment of cancer

(2012) Juan Du et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington’s disease

(2012) Benjamin R. Miller et al.   JOURNAL OF NEUROCHEMISTRY

Species Differences in Reactivity of Mouse and Rat Astrocytes in vitro

(2011) Till B. Puschmann et al.   NEUROSIGNALS

A role for Na+/H+exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane

(2010) Darius J.R. Lane et al.   BIOCHEMICAL JOURNAL

Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron

(2010) Darius J.R. Lane et al.   BIOCHEMICAL JOURNAL

Structure−Activity Relationship Study of First Selective Inhibitor of Excitatory Amino Acid Transporter Subtype 1: 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)

(2010) Mette N. Erichsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Do astrocytes really exocytose neurotransmitters?

(2010) Nicola B. Hamilton et al.   NATURE REVIEWS NEUROSCIENCE

Are there ten times more glia than neurons in the brain?

(2009) Claus C. Hilgetag et al.   Brain Structure & Function

Excitatory amino acid transporters as potential drug targets

(2009) Lennart Bunch et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Ascorbate and plasma membrane electron transport—Enzymes vs efflux

(2009) Darius J.R. Lane et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2

(2009) Fiona E. Harrison et al.   FREE RADICAL BIOLOGY AND MEDICINE

Discovery of the First Selective Inhibitor of Excitatory Amino Acid Transporter Subtype 1

(2009) Anders A. Jensen et al.   JOURNAL OF MEDICINAL CHEMISTRY

A metabolic switch in brain: glucose and lactate metabolism modulation by ascorbic acid

(2009) Maite A. Castro et al.   JOURNAL OF NEUROCHEMISTRY

Ascorbic acid efflux and re-uptake in endothelial cells: maintenance of intracellular ascorbate

(2009) James M. May et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Selective up-regulation of GLT-1 in cultured astrocytes exposed to soluble mediators released by activated microglia

(2009) Sébastien Tilleux et al.   NEUROCHEMISTRY INTERNATIONAL

Development of ascorbate transporters in brain cortical capillary endothelial cells in culture

(2008) Huan Qiao et al.   BRAIN RESEARCH

Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity

(2008) Jianfeng Liang et al.   BRAIN RESEARCH

Identification of a molecular target for glutamate regulation of astrocyte water permeability

(2008) Eli Gunnarson et al.   GLIA

Pharmacological “cross-inhibition” of connexin hemichannels and swelling activated anion channels

(2008) Zu-Cheng Ye et al.   GLIA

Non-transferrin Iron Reduction and Uptake Are Regulated by Transmembrane Ascorbate Cycling in K562 Cells

(2008) Darius J. R. Lane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamate receptors modulate sodium-dependent and calcium-independent vitamin C bidirectional transport in cultured avian retinal cells

(2008) Camila Cabral Portugal et al.   JOURNAL OF NEUROCHEMISTRY

A highly sensitive colorimetric microplate ferrocyanide assay applied to ascorbate-stimulated transplasma membrane ferricyanide reduction and mitochondrial succinate oxidation

(2007) Darius J.R. Lane et al.   ANALYTICAL BIOCHEMISTRY