NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ–IL-27 axis

Activation of Invariant NKT Cells Ameliorates Experimental Ocular Autoimmunity by A Mechanism Involving Innate IFN-  Production and Dampening of the Adaptive Th1 and Th17 Responses

(2014) R. S. Grajewski et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-27 Is a Potent Inducer of IL-10 but Not FoxP3 in Murine T Cells

(2014) M. Batten et al.   JOURNAL OF IMMUNOLOGY

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

(2013) Ivan D Mascanfroni et al.   NATURE IMMUNOLOGY

A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread

(2012) Wolfgang Kastenmüller et al.   CELL

Interleukin-27: Balancing Protective and Pathological Immunity

(2012) Christopher A. Hunter et al.   IMMUNITY

Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1

(2012) Kiyoshi Hirahara et al.   IMMUNITY

Dynamics of NK cell interactionsin vivo

(2012) Jacques Deguine et al.   IMMUNOLOGICAL REVIEWS

Interferon-  mediates chemokine-dependent recruitment of natural killer cells during viral infection

(2012) M. A. Pak-Wittel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

IL-27 Imparts Immunoregulatory Function to Human NK Cell Subsets

(2011) Alice Laroni et al.   PLoS One

Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27

(2011) Caroline Pot et al.   SEMINARS IN IMMUNOLOGY

The Th1 life cycle: molecular control of IFN-γ to IL-10 switching

(2011) Andrew Cope et al.   TRENDS IN IMMUNOLOGY

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

(2010) John Cardone et al.   NATURE IMMUNOLOGY

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

(2010) Roopali Gandhi et al.   NATURE IMMUNOLOGY

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis

(2010) Robert C Axtell et al.   NATURE MEDICINE

Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-  limits IL-17-mediated autoimmune inflammation

(2010) G. Murugaiyan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic behavior of NK cells during activation in lymph nodes

(2009) H. Beuneu et al.   BLOOD

IL-21 Mediates Suppressive Effects via Its Induction of IL-10

(2009) R. Spolski et al.   JOURNAL OF IMMUNOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

Engagement of the Type I Interferon Receptor on Dendritic Cells Inhibits T Helper 17 Cell Development: Role of Intracellular Osteopontin

(2008) Mari L. Shinohara et al.   IMMUNITY

IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice

(2008) Stefan Haak et al.   JOURNAL OF CLINICAL INVESTIGATION

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

(2008) Dror Luger et al.   JOURNAL OF EXPERIMENTAL MEDICINE