Strategies to overcome the barrier: use of nanoparticles as carriers and modulators of barrier properties

Advances in brain drug targeting and delivery: limitations and challenges of solid lipid nanoparticles

(2013) Medha Patel et al.   Expert Opinion on Drug Delivery

Receptor-Mediated Delivery of Magnetic Nanoparticles across the Blood–Brain Barrier

(2012) Ruirui Qiao et al.   ACS Nano

β-Cyclodextrin-poly(β-Amino Ester) Nanoparticles for Sustained Drug Delivery across the Blood–Brain Barrier

(2012) Eun Seok Gil et al.   BIOMACROMOLECULES

Pregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier

(2012) Julia Lemmen et al.   BRAIN RESEARCH

Correlation Analysis of Capillary APOE, VEGF and eNOS Expression in Alzheimer Brains

(2012) J. Provias et al.   Current Alzheimer Research

Exploiting the Properties of Biomolecules for Brain Targeting of Nanoparticulate Systems

(2012) S. Cramer et al.   CURRENT MEDICINAL CHEMISTRY

Anti-Aβ-MAb and dually decorated nanoliposomes: Effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells

(2012) Eleni Markoutsa et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Transport of Poly(n-butylcyano-acrylate) nanoparticles across the blood–brain barrier in vitro and their influence on barrier integrity

(2011) Ralf Rempe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In vitro evidence of dysregulation of blood–brain barrier function after acute and repeated/long-term exposure to TiO2 nanoparticles

(2011) Emilie Brun et al.   BIOMATERIALS

Gelification: An Effective Measure for Achieving Differently Sized Biocompatible Fe3O4Nanocrystals through a Single Preparation Recipe

(2011) Qiaojuan Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Noninvasive, Transient and Selective Blood-Brain Barrier Opening in Non-Human Primates In Vivo

(2011) Fabrice Marquet et al.   PLoS One

Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis

(2011) Mo-Tao Zhu et al.   TOXICOLOGY LETTERS

Strategy for effective brain drug delivery

(2010) M. Intakhab Alam et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Human serum albumin nanoparticles modified with apolipoprotein A-I cross the blood-brain barrier and enter the rodent brain

(2010) Anja Zensi et al.   JOURNAL OF DRUG TARGETING

ApoE3 Mediated Poly(butyl) Cyanoacrylate Nanoparticles Containing Curcumin: Study of Enhanced Activity of Curcumin against Beta Amyloid Induced Cytotoxicity UsingIn VitroCell Culture Model

(2010) Rohit S. Mulik et al.   MOLECULAR PHARMACEUTICS

Brain microvessel endothelial cells responses to gold nanoparticles:In vitropro-inflammatory mediators and permeability

(2010) William J. Trickler et al.   Nanotoxicology

Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release

(2010) Chris Oerlemans et al.   PHARMACEUTICAL RESEARCH

Nanoparticulate Transport of Oximes over an In Vitro Blood-Brain Barrier Model

(2010) Sylvia Wagner et al.   PLoS One

Silver Nanoparticle Induced Blood-Brain Barrier Inflammation and Increased Permeability in Primary Rat Brain Microvessel Endothelial Cells

(2010) William J. Trickler et al.   TOXICOLOGICAL SCIENCES

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Lipid nanocapsules: A new platform for nanomedicine

(2009) N.T. Huynh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Novel Type of Dual-Modality Molecular Probe for MR and Nuclear Imaging of Tumor: Preparation, Characterization and in Vivo Application

(2009) Shujie Liu et al.   MOLECULAR PHARMACEUTICS

Polyalkylcyanoacrylate nanoparticles for delivery of drugs across the blood-brain barrier

(2009) Karine Andrieux et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by the p38 mitogen-activated protein kinase pathway

(2008) Shinya Dohgu et al.   EXPERIMENTAL NEUROLOGY

Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26

(2008) Zhiqing Pang et al.   JOURNAL OF CONTROLLED RELEASE

Lactoferrin-conjugated PEG–PLA nanoparticles with improved brain delivery: In vitro and in vivo evaluations

(2008) Kaili Hu et al.   JOURNAL OF CONTROLLED RELEASE

Manufactured Aluminum Oxide Nanoparticles Decrease Expression of Tight Junction Proteins in Brain Vasculature

(2008) Lei Chen et al.   Journal of Neuroimmune Pharmacology

Bradykinin increases blood–tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton

(2008) Li-bo Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH