Cish actively silences TCR signaling in CD8 + T cells to maintain tumor tolerance

Absence of both Sos-1 and Sos-2 in peripheral CD4+T cells leads to PI3K pathway activation and defects in migration

(2015) Geoffrey Guittard et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Plasticity in programming of effector and memory CD8+T-cell formation

(2015) Ramon Arens et al.   IMMUNOLOGICAL REVIEWS

Adoptive Immunotherapy for Cancer or Viruses

(2014) Marcela V. Maus et al.   Annual Review of Immunology

Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-  on STAT3 and Smads

(2014) K. Tanaka et al.   JOURNAL OF IMMUNOLOGY

A Novel Murine T-Cell Receptor Targeting NY-ESO-1

(2014) Shannon F. Rosati et al.   JOURNAL OF IMMUNOTHERAPY

Type I Cytokines Synergize with Oncogene Inhibition to Induce Tumor Growth Arrest

(2014) N. Acquavella et al.   Cancer Immunology Research

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

(2013) G. P. Linette et al.   BLOOD

Tumour immunology

(2013) Glenn Dranoff et al.   CURRENT OPINION IN IMMUNOLOGY

Transcriptional regulation of effector and memory CD8+ T cell fates

(2013) James ED Thaventhiran et al.   CURRENT OPINION IN IMMUNOLOGY

Adoptive T Cell Transfer for Cancer Immunotherapy in the Era of Synthetic Biology

(2013) Michael Kalos et al.   IMMUNITY

MicroRNA-155 Is Required for Effector CD8+ T Cell Responses to Virus Infection and Cancer

(2013) Jan C. Dudda et al.   IMMUNITY

Engineering improved T cell receptors using an alanine-scan guided T cell display selection system

(2013) Karolina Malecek et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

(2013) Richard A. Morgan et al.   JOURNAL OF IMMUNOTHERAPY

CIS: the late-blooming eldest son

(2013) Akihiko Yoshimura   NATURE IMMUNOLOGY

Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation

(2013) J Adam Best et al.   NATURE IMMUNOLOGY

The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation

(2013) Xuexian O Yang et al.   NATURE IMMUNOLOGY

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Immunotherapy at Large: Balancing tumor immunity and inflammatory pathology

(2013) Glenn Dranoff   NATURE MEDICINE

Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

(2013) B. Chaigne-Delalande et al.   SCIENCE

TCR-Ligand koff Rate Correlates with the Protective Capacity of Antigen-Specific CD8+ T Cells for Adoptive Transfer

(2013) M. Nauerth et al.   Science Translational Medicine

Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses

(2012) A S Chervin et al.   GENE THERAPY

T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

(2012) Carolyn G. King et al.   IMMUNITY

Cell:cell interactions in the immune system

(2012) Facundo D. Batista et al.   IMMUNOLOGICAL REVIEWS

Evaluation of γ-Retroviral Vectors That Mediate the Inducible Expression of IL-12 for Clinical Application

(2012) Ling Zhang et al.   JOURNAL OF IMMUNOTHERAPY

Inhibition of Histone Lysine Methylation Enhances Cancer-Testis Antigen Expression in Lung Cancer Cells: Implications for Adoptive Immunotherapy of Cancer

(2011) M. Rao et al.   CANCER RESEARCH

CD8+ T Cells: Foot Soldiers of the Immune System

(2011) Nu Zhang et al.   IMMUNITY

Association of CISH -292A/T genetic variant with hepatitis B virus infection

(2011) Hoang V. Tong et al.   IMMUNOGENETICS

Immunological perspective of self versus tumor antigens: insights from the RIP-gp model

(2011) Dilan Dissanayake et al.   IMMUNOLOGICAL REVIEWS

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells

(2011) Yun Ji et al.   NATURE IMMUNOLOGY

Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation

(2011) L. Balagopalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts

(2010) S. P. Kerkar et al.   CANCER RESEARCH

Development of Human Anti-Murine T-Cell Receptor Antibodies in Both Responding and Nonresponding Patients Enrolled in TCR Gene Therapy Trials

(2010) J. L. Davis et al.   CLINICAL CANCER RESEARCH

The biologic importance of tumor-infiltrating lymphocytes

(2010) F. Stephen Hodi et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Tumor-Induced Disruption of Proximal TCR-Mediated Signal Transduction in Tumor-Infiltrating CD8+ Lymphocytes Inactivates Antitumor Effector Phase

(2010) E. J. Vazquez-Cintron et al.   JOURNAL OF IMMUNOLOGY

CISHand Susceptibility to Infectious Diseases

(2010) Chiea C. Khor et al.   NEW ENGLAND JOURNAL OF MEDICINE

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

(2009) Soraya Taleb et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function

(2009) Douglas C. Palmer et al.   TRENDS IN IMMUNOLOGY

Loss of CTL Function among High-Avidity Tumor-Specific CD8+ T Cells following Tumor Infiltration

(2008) C. N. Janicki et al.   CANCER RESEARCH

Intercellular Adhesion Molecule-1-Dependent Stable Interactions between T Cells and Dendritic Cells Determine CD8+ T Cell Memory

(2008) Alix Scholer et al.   IMMUNITY

Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity

(2008) D. C. Palmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA