Transgenic mouse models for ADHD

Impaired cliff avoidance reaction in dopamine transporter knockout mice

(2013) Motoyasu Yamashita et al.   PSYCHOPHARMACOLOGY

Attention Deficit/Hyperactivity Disorder-Derived Coding Variation in the Dopamine Transporter Disrupts Microdomain Targeting and Trafficking Regulation

(2012) D. Sakrikar et al.   JOURNAL OF NEUROSCIENCE

Role of Dopamine Receptors in ADHD: A Systematic Meta-analysis

(2012) Jing Wu et al.   MOLECULAR NEUROBIOLOGY

Cortico-Subcortical Neuromodulation Involved in the Amelioration of Prepulse Inhibition Deficits in Dopamine Transporter Knockout Mice

(2012) Yosefu Arime et al.   NEUROPSYCHOPHARMACOLOGY

The Prevalence of DSM-IV Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review

(2012) Erik G. Willcutt   Neurotherapeutics

Diacylglycerol Kinase β Knockout Mice Exhibit Attention-Deficit Behavior and an Abnormal Response on Methylphenidate-Induced Hyperactivity

(2012) Mitsue Ishisaka et al.   PLoS One

Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice

(2012) Peiyan Wong et al.   PLoS One

Neuroimaging of Attention-Deficit/Hyperactivity Disorder: Current Neuroscience-Informed Perspectives for Clinicians

(2012) Samuele Cortese et al.   Current Psychiatry Reports

Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder

(2011) E. Stergiakouli et al.   GENES BRAIN AND BEHAVIOR

Traumatic brain injury and secondary attention-deficit/hyperactivity disorder in children and adolescents: The effect of reward on inhibitory control

(2011) Katia J. Sinopoli et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice

(2011) Hyejung Won et al.   NATURE MEDICINE

Altered Serotonergic Function may Partially Account for Behavioral Endophenotypes in Steroid Sulfatase-deficient Mice

(2011) Simon Trent et al.   NEUROPSYCHOPHARMACOLOGY

Neurobiology of Attention Deficit/Hyperactivity Disorder

(2011) DIANE PURPER-OUAKIL et al.   PEDIATRIC RESEARCH

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

Performance Deficits of NK1 Receptor Knockout Mice in the 5-Choice Serial Reaction-Time Task: Effects of d-Amphetamine, Stress and Time of Day

(2011) Ting Carrie Yan et al.   PLoS One

The lifetime impact of attention deficit hyperactivity disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

(2011) S. Bernardi et al.   PSYCHOLOGICAL MEDICINE

Steroid sulfatase-deficient mice exhibit endophenotypes relevant to Attention Deficit Hyperactivity Disorder

(2011) Simon Trent et al.   PSYCHONEUROENDOCRINOLOGY

Gβ5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems

(2011) Keqiang Xie et al.   PSYCHOPHARMACOLOGY

Polymorphisms of the steroid sulfatase (STS) gene are associated with attention deficit hyperactivity disorder and influence brain tissue mRNA expression

(2010) K.J. Brookes et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Attention-Deficit/Hyperactivity Phenotype in Mice Lacking the Cyclin-Dependent Kinase 5 Cofactor p35

(2010) Justin M. Drerup et al.   BIOLOGICAL PSYCHIATRY

Is the ADHD brain wired differently? A review on structural and functional connectivity in attention deficit hyperactivity disorder

(2010) Kerstin Konrad et al.   HUMAN BRAIN MAPPING

Disorder-specific inferior prefrontal hypofunction in boys with pure attention-deficit/hyperactivity disorder compared to boys with pure conduct disorder during cognitive flexibility

(2010) Katya Rubia et al.   HUMAN BRAIN MAPPING

Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges

(2010) Jacob Eriksen et al.   JOURNAL OF NEUROCHEMISTRY

Role of Aberrant Striatal Dopamine D1 Receptor/cAMP/Protein Kinase A/DARPP32 Signaling in the Paradoxical Calming Effect of Amphetamine

(2010) F. Napolitano et al.   JOURNAL OF NEUROSCIENCE

Dysregulation of Dopamine Transporters via Dopamine D2 Autoreceptors Triggers Anomalous Dopamine Efflux Associated with Attention-Deficit Hyperactivity Disorder

(2010) E. Bowton et al.   JOURNAL OF NEUROSCIENCE

Dopamine transporter inhibition is required for cocaine-induced stereotypy

(2010) Michael R. Tilley et al.   NEUROREPORT

The role of dehydroepiandrosterone (DHEA) in drug-seeking behavior

(2010) Gal Yadid et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Forebrain overexpression of CK1  leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD

(2010) M. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Converging Pharmacological and Genetic Evidence Indicates a Role for Steroid Sulfatase in Attention

(2009) William Davies et al.   BIOLOGICAL PSYCHIATRY

Candidate gene studies of ADHD: a meta-analytic review

(2009) Ian R. Gizer et al.   HUMAN GENETICS

Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk

(2009) Peter L. Oliver et al.   HUMAN MOLECULAR GENETICS

Effects of Modafinil on Dopamine and Dopamine Transporters in the Male Human Brain

(2009) Nora D. Volkow et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Evaluating Dopamine Reward Pathway in ADHD

(2009) Nora D. Volkow et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hyperdopaminergic Tone Erodes Prefrontal Long-Term Potential via a D2 Receptor-Operated Protein Phosphatase Gate

(2009) T.-X. Xu et al.   JOURNAL OF NEUROSCIENCE

Lack of Cocaine Self-Administration in Mice Expressing a Cocaine-Insensitive Dopamine Transporter

(2009) M. Thomsen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

NK1 (TACR1) receptor gene ‘knockout’ mouse phenotype predicts genetic association with ADHD

(2009) TC Yan et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The neuropharmacology of ADHD drugs in vivo: Insights on efficacy and safety

(2009) D.J. Heal et al.   NEUROPHARMACOLOGY

Behavioural and neurochemical abnormalities in mice lacking functional tachykinin-1 (NK1) receptors: A model of attention deficit hyperactivity disorder

(2009) Ting C. Yan et al.   NEUROPHARMACOLOGY

The spontaneously hypertensive rat model of ADHD – The importance of selecting the appropriate reference strain

(2009) Terje Sagvolden et al.   NEUROPHARMACOLOGY

Impaired fear response in mice lacking GIT1

(2009) Robert Schmalzigaug et al.   NEUROSCIENCE LETTERS

Dopamine receptor supersensitivity: Development, mechanisms, presentation, and clinical applicability

(2009) Richard M. Kostrzewa et al.   NEUROTOXICITY RESEARCH

Functional Gene Variation in the Human Norepinephrine Transporter

(2008) Chun-Hyung Kim et al.   Annals of the New York Academy of Sciences

Anomalous Dopamine Release Associated with a Human Dopamine Transporter Coding Variant

(2008) M. S. Mazei-Robison et al.   JOURNAL OF NEUROSCIENCE

The Effects of Methylphenidate on Knockin Mice with a Methylphenidate-Resistant Dopamine Transporter

(2008) M. R. Tilley et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

(2008) Athina Markou et al.   NEUROPSYCHOPHARMACOLOGY

Increased impulsive behavior and risk proneness following lentivirus-mediated dopamine transporter over-expression in rats' nucleus accumbens

(2008) W. Adriani et al.   NEUROSCIENCE

D4 receptor deficiency in mice has limited effects on impulsivity and novelty seeking

(2008) C.M. Helms et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter

(2008) A. Salahpour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA