Microglial carbohydrate-binding receptors for neural repair

 -Glucan Activates Microglia without Inducing Cytokine Production in Dectin-1-Dependent Manner

(2014) V. B. Shah et al.   JOURNAL OF IMMUNOLOGY

Sulfatide, A Major Lipid Component of Myelin Sheath, Activates Inflammatory Responses As an Endogenous Stimulator in Brain-Resident Immune Cells

(2014) S.-B. Jeon et al.   JOURNAL OF IMMUNOLOGY

Sialic Acid on the Neuronal Glycocalyx Prevents Complement C1 Binding and Complement Receptor-3-Mediated Removal by Microglia

(2012) B. Linnartz et al.   JOURNAL OF NEUROSCIENCE

Genetic association of complement receptor 1 polymorphism rs3818361 in Alzheimer’s disease

(2011) Carmen Antúnez et al.   Alzheimers & Dementia

Targeting Siglecs—A novel pharmacological strategy for immuno- and glycotherapy

(2011) Camilla Jandus et al.   BIOCHEMICAL PHARMACOLOGY

The Galβ-(syn)-gauche configuration is required for galectin-recognition disaccharides

(2011) Jun Iwaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells

(2011) A. B. Perez-Oliva et al.   GLYCOBIOLOGY

Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense

(2011) Fabiola Osorio et al.   IMMUNITY

Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes

(2011) Miri Gitik et al.   Journal of Neuroinflammation

The Lipid Sulfatide Is a Novel Myelin-Associated Inhibitor of CNS Axon Outgrowth

(2011) A. M. Winzeler et al.   JOURNAL OF NEUROSCIENCE

Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: a multi-centre case-control study

(2011) Minerva M Carrasquillo et al.   Molecular Neurodegeneration

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Analysis of SM4 sulfatide as a P-selectin ligand using model membranes

(2010) Dirk Simonis et al.   BIOPHYSICAL CHEMISTRY

Complement receptor 1 polymorphisms and risk of late-onset Alzheimer's disease

(2010) Qun Zhang et al.   BRAIN RESEARCH

Alleviation of Neurotoxicity by Microglial Human Siglec-11

(2010) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Signal Regulatory Protein-β1

(2009) Sadanand Gaikwad et al.   AMERICAN JOURNAL OF PATHOLOGY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response

(2009) A. F. Carlin et al.   BLOOD

Transforming growth factor-β1 upregulates keratan sulfate and chondroitin sulfate biosynthesis in microglias after brain injury

(2009) Jiarong Yin et al.   BRAIN RESEARCH

Natural ligands for CD33-related Siglecs?

(2009) A. Varki   GLYCOBIOLOGY

Comparative genomics indicates the mammalian CD33rSiglec locus evolved by an ancient large-scale inverse duplication and suggests all Siglecs share a common ancestral region

(2009) Huan Cao et al.   IMMUNOGENETICS

The expanding roles of ITAM adapters FcRγ and DAP12 in myeloid cells

(2009) Jessica A. Hamerman et al.   IMMUNOLOGICAL REVIEWS

Siglec receptors and hiding plaques in Alzheimer's disease

(2009) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype

(2009) George P Christophi et al.   LABORATORY INVESTIGATION

Strategies in developing promising histone deacetylase inhibitors

(2009) Lei Zhang et al.   MEDICINAL RESEARCH REVIEWS

Cross-regulation of signaling by ITAM-associated receptors

(2009) Lionel B Ivashkiv   NATURE IMMUNOLOGY

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

Expression of galectin-1 in immune cells and glial cells after spinal cord injury

(2009) Dai Kurihara et al.   NEUROSCIENCE RESEARCH

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

SIGLEC16encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpartSIGLEC11and has functional and non-functional alleles in humans

(2008) Huan Cao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease

(2008) D. Farfara et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling

(2008) Jennifer S. Ziegenfuss et al.   NATURE

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

Location, location, location: identifying the neighborhoods of LPS signaling

(2008) Colin Watts   NATURE IMMUNOLOGY

Axon regeneration inhibitors

(2008) Lynda J.-S. Yang et al.   NEUROLOGICAL RESEARCH

Evaled Expression of ICAM-1 and Its Ligands in the Rat Spinal Cord Following Lipopolysaccharide Intraspinal Injection

(2008) Junling Yang et al.   NEUROMOLECULAR MEDICINE

Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation

(2008) Asya Rolls et al.   PLOS MEDICINE