Proteases, cystic fibrosis and the epithelial sodium channel (ENaC)

The Facilitating Effect of Hypertonic Saline on Resolution of Airway Inflammation in Cystic Fibrosis

(2013) Emer P. Reeves et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of the epithelial sodium channel in salt-sensitive hypertension

(2011) Yan Sun et al.   ACTA PHARMACOLOGICA SINICA

Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients

(2011) BAOLERI LEE et al.   APMIS

Direct Evaluation of Pseudomonas aeruginosa Biofilm Mediators in a Chronic Infection Model

(2011) Matthew S. Byrd et al.   INFECTION AND IMMUNITY

New families of carboxyl peptidases: serine-carboxyl peptidases and glutamic peptidases

(2011) K. Oda   JOURNAL OF BIOCHEMISTRY

Calcium-induced Folding and Stabilization of thePseudomonas aeruginosaAlkaline Protease

(2011) Liang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

(2011) Zhe Zhou et al.   Journal of Cystic Fibrosis

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2011) N. D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

An Activated Immune and Inflammatory Response Targets the Pancreas of Newborn Pigs with Cystic Fibrosis

(2011) Maisam Abu-El-Haija et al.   PANCREATOLOGY

Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na+ transport in response to apical fluid volume expansion in human H441 airway epithelial cells

(2011) Chong D. Tan et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Human cystic fibrosis airway epithelia have reduced Cl- conductance but not increased Na+ conductance

(2011) O. A. Itani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute Regulation of the Epithelial Sodium Channel in Airway Epithelia by Proteases and Trafficking

(2010) Michael M. Myerburg et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Regulation of the epithelial sodium channel (ENaC) by membrane trafficking

(2010) Michael B. Butterworth   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases

(2010) Nicolas Guyot et al.   BIOLOGICAL CHEMISTRY

Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia

(2010) Jeng-Haur Chen et al.   CELL

SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) inXenopus laevisoocytes

(2010) Brett M. Rollins et al.   Channels

A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+self inhibition

(2010) Robert Rauh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases

(2010) Erol A. Gaillard et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Functional Characterization of a Partial Loss-of-Function Mutation of the Epithelial Sodium Channel (ENaC) Associated with Atypical Cystic Fibrosis

(2009) Regina Huber et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Regulation of sodium transport by ENaC in the kidney

(2009) L Lee Hamm et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Gene expression characteristics of a cystic fibrosis epidemic strain ofPseudomonas aeruginosaduring biofilm and planktonic growth

(2009) Jim Manos et al.   FEMS MICROBIOLOGY LETTERS

Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease

(2009) Abul Kalam Azad et al.   HUMAN MUTATION

Transcriptional Regulation of Mouse Mast Cell Protease-2 by Interleukin-15

(2009) Farhad Mirghomizadeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

(2009) Thomas R. Kleyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How intramembrane proteases bury hydrolytic reactions in the membrane

(2009) Elinor Erez et al.   NATURE

MEROPS: the peptidase database

(2009) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Activation of the Epithelial Sodium Channel (ENaC) by Serine Proteases

(2008) Bernard C. Rossier et al.   Annual Review of Physiology

The Contribution of Epithelial Sodium Channels to Alveolar Function in Health and Disease

(2008) Douglas C. Eaton et al.   Annual Review of Physiology

Airway Inflammation in Cystic Fibrosis

(2008) Arnon Elizur et al.   CHEST

Inhibition of airway proteases in cystic fibrosis lung disease

(2008) M. Griese et al.   EUROPEAN RESPIRATORY JOURNAL

Proteases and cystic fibrosis

(2008) J VOYNOW et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of Cilia, Mucus, and Airway Surface Liquid in Mucociliary Dysfunction: Lessons from Mouse Models

(2008) Marcus A. Mall   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Elafin, an Elastase-specific Inhibitor, Is Cleaved by Its Cognate Enzyme Neutrophil Elastase in Sputum from Individuals with Cystic Fibrosis

(2008) Nicolas Guyot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmin Activates Epithelial Na+Channels by Cleaving the γ Subunit

(2008) Christopher J. Passero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preferential Assembly of Epithelial Sodium Channel (ENaC) Subunits inXenopusOocytes

(2008) Michael Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteases: Multifunctional Enzymes in Life and Disease

(2008) Carlos López-Otín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lung

(2008) J. Manos et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Mechanisms of ENaC Regulation and Clinical Implications

(2008) V. Bhalla et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Degradome database: mammalian proteases and diseases of proteolysis

(2008) V. Quesada et al.   NUCLEIC ACIDS RESEARCH

Neutrophils in cystic fibrosis

(2008) D G Downey et al.   THORAX

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY