Dysfunction of TGF-β1 signaling in Alzheimer’s disease: perspectives for neuroprotection

Potent Anti-Inflammatory and Neuroprotective Effects of TGF- 1 Are Mediated through the Inhibition of ERK and p47phox-Ser345 Phosphorylation and Translocation in Microglia

(2014) L. Qian et al.   JOURNAL OF IMMUNOLOGY

Transforming Growth Factor-β Signaling in Motor Neuron Diseases

(2011) M. Katsuno et al.   CURRENT MOLECULAR MEDICINE

Epidemiology of Alzheimer disease

(2011) Christiane Reitz et al.   Nature Reviews Neurology

The Monomer State of Beta-Amyloid: Where the Alzheimer's Disease Protein Meets Physiology

(2011) M.L. Giuffrida et al.   REVIEWS IN THE NEUROSCIENCES

Neurosteroids and Hepatic Encephalopathy: An Update on Possible Pathophysiologic Mechanisms

(2011) Samir Ahboucha   Current Molecular Pharmacology

Transgenic Mice Overexpressing APP and Transforming Growth Factor-β1 Feature Cognitive and Vascular Hallmarks of Alzheimer's Disease

(2010) Brice Ongali et al.   AMERICAN JOURNAL OF PATHOLOGY

miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer's disease targets TGF-β type II receptor

(2010) Hailin Wang et al.   BRAIN RESEARCH

Pathological implications of cell cycle re-entry in Alzheimer disease

(2010) David J. Bonda et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Early defect of transforming growth factor β1 formation in Huntington’s disease

(2010) Giuseppe Battaglia et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TGF-β1 blockade of microglial chemotaxis toward Aβ aggregates involves SMAD signaling and down-regulation of CCL5

(2010) Wei-Chao Huang et al.   Journal of Neuroinflammation

Psychopharmacological Neuroprotection in Neurodegenerative Disease: Assessing the Preclinical Data

(2010) E. C. Lauterbach et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Reimagining Alzheimer's Disease--An Age-Based Hypothesis

(2010) K. Herrup   JOURNAL OF NEUROSCIENCE

Transforming growth factor beta and soluble endoglin in the healthy senior and in Alzheimer’s disease patients

(2010) B. Juraskova et al.   Journal of Nutrition Health & Aging

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer's Disease: Selective Activation of mGlu2 Receptors Amplifies  -Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective

(2010) F. Caraci et al.   MOLECULAR PHARMACOLOGY

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Microglial alterations in human Alzheimer's disease following Aβ42 immunization

(2010) E. Zotova et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

GROWTH FACTORS DECREASE IN SUBJECTS WITH MILD TO MODERATE ALZHEIMER'S DISEASE (AD): POTENTIAL CORRECTION WITH DEHYDROEPIANDROSTERONE-SULPHATE (DHEAS)

(2009) C. Luppi et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

TGF-β1 Pathway as a New Target for Neuroprotection in Alzheimer's Disease

(2009) Filippo Caraci et al.   CNS Neuroscience & Therapeutics

NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease

(2009) Nicholas H. Varvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Lithium Trial in Alzheimer's Disease

(2009) Harald Hampel et al.   JOURNAL OF CLINICAL PSYCHIATRY

Bioactive TGF-β can associate with lipoproteins and is enriched in those containing apolipoprotein E3

(2009) Ina Tesseur et al.   JOURNAL OF NEUROCHEMISTRY

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY

 -Amyloid Monomers Are Neuroprotective

(2009) M. L. Giuffrida et al.   JOURNAL OF NEUROSCIENCE

Microglial activation and amyloid deposition in mild cognitive impairment: A PET study

(2009) A. Okello et al.   NEUROLOGY

Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation

(2009) Hung-Ming Wu et al.   NEUROPSYCHOPHARMACOLOGY

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

(2008) C.-X. Gong et al.   CURRENT MEDICINAL CHEMISTRY

A  Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease

(2008) N. H. Varvel et al.   JOURNAL OF NEUROSCIENCE

Lithium may be useful in the prevention of Alzheimer’s disease in individuals at risk of presenile familial Alzheimer’s disease

(2008) Heng-Liang Yeh et al.   MEDICAL HYPOTHESES

TGF-β1 protects against Aβ-neurotoxicity via the phosphatidylinositol-3-kinase pathway

(2008) Filippo Caraci et al.   NEUROBIOLOGY OF DISEASE

Enhanced expression of ERα in astrocytes modifies the response of cortical neurons to β-amyloid toxicity

(2008) Viviana Carbonaro et al.   NEUROBIOLOGY OF DISEASE

Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease

(2007) Leonel E. Rojo et al.   ARCHIVES OF MEDICAL RESEARCH