Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination

(2014) A. Zahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of AID, the B-cell genome mutator

(2013) C. Keim et al.   GENES & DEVELOPMENT

Endogenous APOBEC3A DNA Cytosine Deaminase Is Cytoplasmic and Nongenotoxic

(2013) Allison M. Land et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuating homologous recombination stimulates an AID-induced antileukemic effect

(2013) Kristin R. Lamont et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1

(2013) Qingxiang Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of activation-induced deaminase in Lupus Nephritis

(2012) Marilyn Diaz   AUTOIMMUNITY

The APOBEC3C crystal structure and the interface for HIV-1 Vif binding

(2012) Shingo Kitamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activation induced deaminase: How much and where?

(2012) Alexandre Orthwein et al.   SEMINARS IN IMMUNOLOGY

Combinatorial mechanisms regulating AID-dependent DNA deamination: Interacting proteins and post-translational modifications

(2012) Bao Q. Vuong et al.   SEMINARS IN IMMUNOLOGY

The cytoplasmic AID complex

(2012) Julien Häsler et al.   SEMINARS IN IMMUNOLOGY

Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1

(2011) Alexandre Orthwein et al.   EMBO JOURNAL

REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase

(2011) Yasuhiro Uchimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1  (eEF1A)

(2011) J. Hasler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

eEF1A: Thinking Outside the Ribosome

(2010) Maria K. Mateyak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90

(2010) Alexandre Orthwein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of Reptilian APOBEC1 Suggests that RNA Editing May Not Be Its Ancestral Function

(2010) Francesco Severi et al.   MOLECULAR BIOLOGY AND EVOLUTION

Inhibition of translation by cytotrienin A--a member of the ansamycin family

(2010) L. Lindqvist et al.   RNA

AID Produces DNA Double-Strand Breaks in Non-Ig Genes and Mature B Cell Lymphomas with Reciprocal Chromosome Translocations

(2009) Davide F. Robbiani et al.   MOLECULAR CELL

Active nuclear import and cytoplasmic retention of activation-induced deaminase

(2009) Anne-Marie Patenaude et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Altering Chemosensitivity by Modulating Translation Elongation

(2009) Francis Robert et al.   PLoS One

The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence

(2009) R. Geisberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macromolecular Modeling with Rosetta

(2008) Rhiju Das et al.   Annual Review of Biochemistry

Proteasomal degradation restricts the nuclear lifespan of AID

(2008) Said Aoufouchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Two Regions within the Amino-Terminal Half of APOBEC3G Cooperate To Determine Cytoplasmic Localization

(2008) M. D. Stenglein et al.   JOURNAL OF VIROLOGY

eEF1A Is a Novel Component of the Mammalian Nuclear Protein Export Machinery

(2008) Mireille Khacho et al.   MOLECULAR BIOLOGY OF THE CELL