Journal
CELL
Volume 149, Issue 6, Pages 1179-1181Publisher
CELL PRESS
DOI: 10.1016/j.cell.2012.05.013
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Mutations in keratinocyte and melanocyte precursors that are caused by extensive sun exposure are well-established contributors to skin cancer. Now Hu et al. provide evidence that the sun's harmful rays may also cause tumor-promoting epigenetic modifications in dermal fibroblasts, high-lighting further the importance of tumor-stroma interactions in cancer.
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