Journal
CELL
Volume 135, Issue 5, Pages 779-785Publisher
CELL PRESS
DOI: 10.1016/j.cell.2008.11.009
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Funding
- Howard Hughes Medical Institute Funding Source: Medline
- NIGMS NIH HHS [R01 GM038499, R01 GM038499-17] Funding Source: Medline
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As transforming as the first atomic resolution view of myoglobin in the late 1950s, scientists can now use a suite of single molecule technologies to watch protein macromolecular machines executing their functions in real time. This Essay highlights applications and challenges of single molecule studies in structural biology, cell biology, and biotechnology.
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