Review
Cardiac & Cardiovascular Systems
Veronica Romano, Carlo Maria Gallinoro, Rosita Mottola, Alessandro Serio, Franca Di Meglio, Clotilde Castaldo, Felice Sirico, Daria Nurzynska
Summary: The article summarizes the developmental and anatomical features of patent foramen ovale (PFO) and discusses the clinical risks associated with this atrial septal defect in adults.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2021)
Article
Biochemistry & Molecular Biology
Zhen Yuan, Long-Zhen Zhang, Bin Li, Hung-Tao Chung, Jin-Xin Jiang, John Y. Chiang, Hsin-Ju Chiang, Hon-Kan Yip, Pei-Hsun Sung
Summary: Persistent patent foramen ovale (PFO) and patent ductus arteriosus (PDA) in newborns show differences in characteristics and concomitant congenital defects. Over 95% of newborns with PFO or PDA close spontaneously at 6 months, while persistent PFO or PDA is strongly associated with complex congenital heart disease. Regular long-term monitoring is required for future complications.
BIOMEDICAL JOURNAL
(2021)
Review
Cardiac & Cardiovascular Systems
Gianluca Rigatelli, Marco Zuin, Claudio Bilato
Summary: This systematic review and meta-analysis found that atrial septal aneurysms (ASA) play an important role in cryptogenic stroke (CS) in patients with patent foramen ovale (PFO), but its contribution is still not fully clarified in current literature.
TRENDS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Yi Song, Hang Xing, Peter David Koch, Xiaofei Li, Yan Zhang
Summary: This study systematically reviewed the feasibility and safety of combining closure of PFO/ASD and left atrial appendage. The results showed that combining PFO/ASD occlusion and left atrial appendage closure had similar procedural success rate and safety outcomes compared to single left atrial appendage closure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Medicine, General & Internal
Heng Sun, Chang Zhou, Liang Xu, Tao Xu
Summary: The study revealed that atrial septal abnormalities can increase the risk of atrial vulnerability, and atrial arrhythmia caused by atrial septal abnormalities may be one of the mechanisms of cryptogenic stroke.
Article
Medical Informatics
Laura Oliva, Eric Horlick, Bo Wang, Ella Huszti, Ruth Hall, Lusine Abrahamyan
Summary: This study developed a machine-learning based algorithm to differentiate between patients with patent foramen ovale (PFO) and atrial septal defects (ASD) in healthcare administrative data. The final model achieved reasonable accuracy, sensitivity, and specificity, suggesting its potential usefulness in evaluating long-term closure outcomes of PFO and ASD.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2022)
Article
Medicine, General & Internal
Giuseppe Verolino, Dario Calderone, Mara Gavazzoni, Davide Sala, Paolo Sganzerla
Summary: The study investigated the performance of the GORE Septal Occluder in PFO closure procedures and found a high closure rate across different anatomies. The GSO system demonstrated effective closure for PFO patients with varying widths and tunnel lengths.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Yuta Hoshina, Hiroyuki Iijima, Mitsuru Kubota, Tsutomu Murakami, Akira Nagai
Summary: The study reported a case in which closure of atrial septal defect effectively relieved migraine headaches, highlighting the association between the two conditions and the potential benefits of the procedure.
CLINICAL CASE REPORTS
(2022)
Review
Cardiac & Cardiovascular Systems
Davor Vukadinovic, Bruno Scheller, Christian Ukena, Sebastian Ewen, Felix Mahfoud, Michael Bohm
Summary: There is a significant difference in the risk of AF after PFO closure between Amplatzer PFO Occluder and GORE Occluder, with the former having a lower incidence rate. However, these findings need to be validated in a large-scale randomized clinical trial.
CLINICAL RESEARCH IN CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Dominik Jurczyk, Sascha Macherey-Meyer, Elias Rawish, Thomas Stiermaier, Ingo Eitel, Christian Frerker, Tobias Schmidt
Summary: This study aimed to determine the incidence rates of new-onset atrial fibrillation (AF) after percutaneous closure of patent foramen ovale (PFO) and investigate the differences due to various screening strategies and devices. The meta-analysis showed that percutaneous PFO closure led to a higher incidence of AF compared to conservative treatment. However, the heterogeneity in surveillance and follow-up strategies limited the generalizability of the findings.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Clinical Neurology
Davide Strambo, Gaia Sirimarco, Stefania Nannoni, Kalliopi Perlepe, George Ntaios, Kostantinos Vemmos, Patrik Michel
Summary: The study verifies the effectiveness of the RoPE score in predicting the presence/absence of PFO in ESUS patients and suggests that the RoPE score is helpful in distinguishing between pathogenic and incidental PFOs. Factors such as left ventricular hypertrophy, atherosclerosis, and infratentorial stroke may enhance the score, while lower RoPE scores are associated with more incidental atrial fibrillation during a 10-year follow-up.
Article
Cardiac & Cardiovascular Systems
Mariel E. Turner, Ismail Bouhout, Christopher J. Petit, David Kalfa
Summary: The field of congenital interventional cardiology has grown significantly in recent years, with percutaneous device closure becoming a mainstay of treatment for many septal defects. This review discusses the current state, patient selection, procedural approach, and outcomes of transcatheter closure of atrial septal defects (ASDs) and ventricular septal defects (VSDs) in children and adults, as well as potential areas for future evolution and innovation.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Christian Valdemar Skibsted, Kasper Korsholm, Lars Pedersen, Kasper Bonnesen, Jens Erik Nielsen-Kudsk, Morten Schmidt
Summary: This study investigated the long-term risk of developing atrial fibrillation (AF) following transcatheter closure of patent foramen ovale (PFO). The results showed that compared to the PFO diagnosis group without surgery, the PFO closure group had an increased risk of developing AF within the first 3 months, but there was no significant long-term risk increase after the surgery.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Laura Oliva, Ella Huszti, Ruth Hall, Lusine Abrahamyan, Eric Horlick
Summary: The incidence of new-onset AF after PFO closure was relatively low. Having diabetes and age>60 years were the most important factors associated with new-onset AF in this population.
Article
Hematology
Ioannis A. Leventis, Dimitrios Sagris, Davide Strambo, Kalliopi Perlepe, Gaia Sirimarco, Stefania Nannoni, Eleni Korompoki, Efstathios Manios, Konstantinos Makaritsis, Konstantinos Vemmos, Patrik Michel, George Ntaios
Summary: The presence of atrial cardiopathy is inversely related to the presence of likely pathogenic PFO in patients with ESUS, with lower prevalence rates in ESUS patients compared to other conditions.
THROMBOSIS AND HAEMOSTASIS
(2021)
