Article
Chemistry, Multidisciplinary
Angus Olding, Curtis C. Ho, Allan J. Canty, Nigel T. Lucas, James Horne, Alex C. Bissember
Summary: This study reports the synthesis of a family of unprecedented arylpalladium(II) boronates that are kinetically stable at ambient temperature, and their chemical competence in a Suzuki-Miyaura reaction was demonstrated.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Elvis N. Nishida, Elder C. Leopoldino, Laize Zaramello, Higor A. Centurion, Renato Goncalves, Ricardo F. Affeldt, Carlos E. M. Campos, Bruno S. Souza
Summary: A novel Pd(II)-polymeric pre-catalyst was successfully prepared and demonstrated good activity in the Suzuki-Miyaura coupling reaction. The catalyst showed recyclability and its performance was affected by the concentration of the cross-coupling partners. The presence of oxygen was found to be crucial in preventing the formation of inactive Pd(0) aggregates.
Article
Chemistry, Multidisciplinary
Julius Hoepfner, Marius Brehm, Pavel A. Levkin
Summary: The rising costs of pharmaceutical research are currently limiting the productivity of drug discovery and development, but can potentially be reduced through miniaturization of compound synthesis and screening. In this study, the influential palladium-catalyzed Suzuki-Miyaura reaction is successfully implemented at the nanoliter scale on droplet microarrays for the synthesis of an 800-compound library of biphenyls. The synthesis of these compounds requires minimal reagents and solvent volume, and the obtained compounds can be purified and cleaved from excess reactants and catalyst. This novel approach expands the capabilities of droplet microarrays for miniaturized high-throughput chemical synthesis and opens up possibilities for future synthesis and screening of chemical compounds in a single platform.
Article
Chemistry, Inorganic & Nuclear
Ceren Akpunar, Namik Ozdemir, Mert Olgun Karatas, Bulent Alici, Ismail Ozdemir
Summary: In this study, we synthesized five new coumarin-functionalised PEPPSI type Pd-NHC complexes to examine their catalyst properties. The complexes showed slightly distorted square-planar geometry and exhibited catalytic activity in the Suzuki-Miyaura reaction of phenylboronic acid and aryl bromide derivatives.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Maryam Mohammadikish, Nazanin Mosleh
Summary: Utilizing sunlight as a driving force in chemical reactions is beneficial for sustainability. This study reports the synthesis of a graphitic-carbon nitride system modified with Pd nanoparticles, which exhibits prominent photocatalytic performance for Suzuki-Miyaura coupling reactions.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Applied
Liam Byrne, Christian Skold, Per-Ola Norrby, Rachel H. Munday, Andrew R. Turner, Peter D. Smith
Summary: The development of biaryl 2,5-diphenylphospholanes as a new class of C-2-symmetric, monodentate ligands for asymmetric Suzuki-Miyaura (ASM) reactions has led to the successful preparation of a range of atropisomeric biaryl and heterobiaryl products with good to excellent levels of enantioselectivity. DFT studies indicate that the formation of a constraining ligand pocket and coordination of one of the biaryl methoxy groups to the metal center in the optimized ligands are crucial for restricting conformational freedom in the bond-forming step.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Multidisciplinary
Shiguang Pan, Cong Gao, Jiatong Gui, Beibei Hu, Lifeng Gai, Changsheng Qiao, Chengwei Liu
Summary: A hierarchical titanium dioxide microspheres-supported palladium catalyst (Pd/TiO2-350) was successfully prepared and characterized. The Pd immobilization on TiO2 was confirmed with a palladium loading of 0.1 mmol g(-1) by ICP-OES analysis. Pd/TiO2-350 efficiently catalyzed the Suzuki-Miyaura reaction and could be reused multiple times without significant loss of activity, with a decreased loading of palladium species to 0.001 mol% and high turnover number and turnover frequency of 99,000 and 0.57 s(-1), respectively.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Alexander F. Schmidt, Anna A. Kurokhtina, Elizaveta Larina, Nadezhda A. Lagoda
Summary: Despite extensive studies on the reaction of Pd intermediates in the Suzuki-Miyaura reaction (SMR), direct evidence supporting the widely accepted assumptions regarding the activity of Pd hydroxo complexes is lacking. This study presents results on the reactivity of Pd-OH and/or Pd-OR-containing complexes in the transmetalation step under ligand-free turnover conditions. The catalytic involvement of specific Pd species was determined under real catalytic conditions by measuring the selectivity of competing reactions.
MOLECULAR CATALYSIS
(2023)
Article
Chemistry, Physical
Tiefeng Xu, Panting Lu, Sebastian Wohlrab, Wenxing Chen, Armin Springer, Xiao-Feng Wu, Wangyang Lu
Summary: Pd nanoparticles supported on low-melting polyester fabric were synthesized via a microwave-assisted method, showing excellent catalytic activity in Suzuki-Miyaura coupling reactions. The fabric can be conveniently separated from the reaction mixture and maintains good catalytic performance after 8 cycles, without Pd leaching.
CATALYSIS COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Saeed Bahadorikhalili, Leila Ma'mani, Hosein Lijan, Mohammad Mahdavi
Summary: A novel nanocatalyst, gamma-Fe2O3@SiO2(CH2)(3)-HPBM-Pd, was designed and synthesized for Mizoroki-Heck and Suzuki-Miyaura crosscoupling reactions, showing excellent activity and high reusability with a catalyst turnover number of 4600 in 10 sequential runs.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Kanticha Khomthawee, Nattaporn Nilada, Antika Homchuen, Pranorm Saejueng
Summary: The CS-EDTA-Pd catalyst was prepared by dissolving chitosan and EDTA in acetic acid, forming beads, adsorbing palladium(II), and reducing it to palladium(0) with ethanol reflux. The catalyst was characterized by various techniques. It was then tested in the Suzuki-Miyaura cross-coupling reaction and showed good catalytic activity. The catalyst is inexpensive, easy to prepare, and can be reused multiple times with only a slight loss in product yields.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Applied
Andrei Baran, Mariia Babkova, Jana Petkus, Kirill Shubin
Summary: A convenient and general method for Suzuki-Miyaura double cross-coupling of various dibromothiophenes was developed. Using a simple and cheap catalytic system, diarylthiophenes, useful in the synthesis of metal-organic frameworks (MOFs), can be obtained in moderate to excellent yields. The efficiency of the catalytic process and excess of boronic acids help to suppress side products and simplify the purification of products.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Review
Chemistry, Physical
Gianluigi Albano, Antonella Petri, Laura Antonella Aronica
Summary: In recent years, there has been extensive research on immobilizing palladium nanoparticles on solid supports for the preparation of active and stable catalytic systems. Compared to inorganic materials, naturally occurring organic solids are more cost-effective and readily available. This review focuses on the application of metal catalysts supported by natural biomaterials in C-C bond formation reactions, specifically Mizoroki-Heck, Suzuki-Miyaura, and Sonogashira reactions. Different types of organic matrices, such as cellulose, starch, pectin, agarose, chitosan, as well as proteins and enzymes, are discussed, highlighting the heterogeneous nature and recyclability of each catalyst.
Article
Chemistry, Multidisciplinary
Sheng-Qi Qiu, Yu Chen, Xiang-Jun Peng, Shi-Jiang He, Jun Kee Cheng, Yong-Bin Wang, Shao-Hua Xiang, Jun Song, Peiyuan Yu, Junmin Zhang, Bin Tan
Summary: In this study, we achieved the arene-alkene Suzuki-Miyaura coupling reaction between hindered aryl halides and vinyl boronates by designing appropriate ligands and reaction parameters. The axially chiral acyclic aryl-alkenes obtained exhibited remarkable efficiency, enantioselectivity, and E/Z selectivity.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Polymer Science
Ameneh Ahmadi, Tahereh Sedaghat, Roya Azadi
Summary: In this study, a Palladium-based magnetic nanocomposite was synthesized and utilized as a catalyst for Suzuki coupling and Heck-Mizoroki coupling reactions, demonstrating efficient catalytic activity and recyclability.
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Daniel Hofmann, Ralf Thomann, Rolf Muelhaupt
MACROMOLECULAR MATERIALS AND ENGINEERING
(2018)
Article
Materials Science, Multidisciplinary
Fan Zhong, Ralf Thomann, Rolf Muelhaupt
MACROMOLECULAR MATERIALS AND ENGINEERING
(2018)
Article
Chemistry, Multidisciplinary
Sergej Repp, Ersan Harputlu, Seda Gurgen, Mike Castellano, Nora Kremer, Nils Pompe, Jakob Woerner, Anke Hoffmann, Ralf Thomann, Fatih M. Emen, Stefan Weber, Kasim Ocakoglu, Emre Erdem
Article
Polymer Science
Fan Zhong, Jeremia Schwabe, Ralf Thomann, Rolf Muelhaupt
MACROMOLECULAR RAPID COMMUNICATIONS
(2019)
Article
Polymer Science
Fan Zhong, Ralf Thomann, Rolf Muelhaupt
Article
Polymer Science
Alexander Kozur, Laura Burk, Ralf Thomann, Pierre J. Lutz, Rolf Muelhaupt
Article
Polymer Science
Fan Zhong, Ralf Thomann, Yi Thomann, Laura Burk, Rolf Muelhaupt
Article
Chemistry, Multidisciplinary
Jasmin-Clara Buerger, Sebastian Gutsch, Yi Thomann, Ralf Thomann, Bjoern Christian, Oliver Ambacher, Margit Zacharias
Summary: This study discusses the experimental tuning of freestanding SnO2 nanowires growth to a laterally aligned nanowire growth mode, with thermodynamic considerations for influencing parameters. The research shows that a continuous gold film inhibits the laterally aligned growth, leading to growth only at the edges while the central region is covered by freestanding wires.
CRYSTAL GROWTH & DESIGN
(2021)
Article
Chemistry, Physical
Maria Isabel Sierra-Trillo, Ralf Thomann, Ingo Krossing, Ralf Hanselmann, Rolf Muelhaupt, Yi Thomann
Summary: By using high peak power nanosecond-pulsed infrared laser, we found that toluene as a liquid medium is an effective method for producing micrometer-sized graphene material, while water is less ideal.
Article
Nanoscience & Nanotechnology
Benedikt Deuringer, Carmen Haerdtner, Katja Krebs, Ralf Thomann, Martin Holzer, Ingo Hilgendorf, Regine Suess
Summary: The conventional techniques for rHDL preparation have limitations, including long process times and harsh preparation conditions. This study presents a novel method to overcome these challenges and proposes a dual mode of action for Eve-rHDL in atherosclerosis and cardiovascular disease.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Engineering, Biomedical
Artem Egorov, Bianca Riedel, Johannes Vinke, Hagen Schmal, Ralf Thomann, Yi Thomann, Michael Seidenstuecker
Summary: In this study, different calcification methods for collagen and collagen coatings were compared for their suitability for 3D printing and production of collagen-coated scaffolds. HA directly in the collagen solution resulted in increased viscosity and led to clumping on the scaffolds. The incubation and ALP coating methods resulted in increased HA layer thickness, while no coating on the collagen layer was observed with the poly-L-aspartic acid method.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Kun Dai, Mahesh D. Pol, Lenard Saile, Arti Sharma, Bin Liu, Ralf Thomann, Johanna L. Trefs, Danye Qiu, Sandra Moser, Stefan Wiesler, Bizan N. Balzer, Thorsten Hugel, Henning J. Jessen, Charalampos G. Pappas
Summary: The mechanisms of spontaneous and selective peptide elongation in aqueous abiotic systems remain unclear. This study used aminoacyl phosphate esters to uncover these pathways. The phosphate esters acted as solubility tags, allowing hydrophobic amino acids and their oligomers to be soluble in water and enabling selective elongation and different pathways to emerge.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Electrochemistry
Witali Beichel, Julian Skrotzki, Petra Klose, Christian Njel, Burkhard Butschke, Stephan Burger, Lili Liu, Ralf Thomann, Yi Thomann, Daniel Biro, Simon Thiele, Ingo Krossing
Summary: A study found that Li electrodes treated with the phosphoric-acid derivative HBFEP exhibit self-healing ability and an extended cycle lifetime. This treatment method shows promising performance in Li-Li symmetrical cells, potentially enhancing the rechargeability of Li electrodes.
BATTERIES & SUPERCAPS
(2022)
Article
Chemistry, Physical
Szabolcs Pasztor, Balint Becsei, Gyorgyi Szarka, Yi Thomann, Ralf Thomann, Rolf Muehlhaupt, Bela Ivan
Meeting Abstract
Chemistry, Multidisciplinary
Bela Ivan, Szabolcs Pasztor, Csaba Fodor, Marton Haraszti, Gergely Kali, Yi Thomann, Ralf Thomann, Rolf Muelhaupt
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)
