Article
Chemistry, Multidisciplinary
Andrea Porcheddu, Rita Mocci, Margherita Brindisi, Federico Cuccu, Claudia Fattuoni, Francesco Delogu, Evelina Colacino, Maria Valeria D'Auria
Summary: An environmentally friendly mechanochemical protocol was developed to synthesize indoles and indolines using oxalic acid and dimethylurea. The solvent-free procedure showed versatility and wide scope, leading to variously decorated compounds. The methodology also has potential for preparing compounds of pharmaceutical interest.
Article
Chemistry, Multidisciplinary
Lea Spitzer, Sebastien Lecommandoux, Henri Cramail, Francois Jerome
Summary: An efficient method has been developed to synthesize end-functionalized oligosaccharides from unprotected monosaccharides, using a one-pot/two-step approach. The monosaccharides were first functionalized with an alkyne group at the anomeric position, then oligomerized to reach a DPn of up to 8. The obtained oligosaccharides showed complete propargylation and could be coupled to oleic acid to produce bio-based surfactants.
Article
Chemistry, Multidisciplinary
Dawei Dong, Yafei Xiao, Minghua Zhang, Peixin Gong, Yingqing Ye, Shuhua Peng, Ke Wang, Minmin Fan
Summary: Polysaccharide is a complex biological macromolecule that plays an irreplaceable role in organisms. This study synthesized glucan polysaccharide using a green and efficient solid-phase polymerization method, and characterized the resulting product. It was found to have mainly linear structure with various glycosidic linkages.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Review
Chemistry, Multidisciplinary
Matteo Haese, Kai Winterhalter, Jessica Jung, Magnus S. Schmidt
Summary: This review summarizes the advancements and applications of Fischer glycosylation in the synthesis of glycosides over the past 15 years.
TOPICS IN CURRENT CHEMISTRY
(2022)
Article
Chemistry, Organic
Niels R. M. Reintjens, Martin D. Witte, Adriaan J. Minnaard
Summary: Thioglycosides or S-linked-glycosides are important glycomimetics that can be synthesized by glycosylating deoxythio sugar acceptors. A carbonyl group formed by site-selective oxidation of unprotected saccharides can be converted into a thiol moiety, allowing for the preparation of deoxythio sugars through S(N)1 substitution reactions. The combination of these deoxythio sugars with protecting group-free glycosylation of glycosyl fluorides enables a protecting group-free synthesis of thioglycosides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Hatem M. Altass, Moataz Morad, Abdelrahman S. Khder, Mohamed Raafat, Reem Alsantali, Menna A. Khder, Reda S. Salama, M. Shaheer Malik, Ziad Moussa, Mohammed A. S. Abourehab, Saleh A. Ahmed
Summary: Solid acidic cerium tungstate catalysts with different molar ratios of cerium and tungstate were prepared using direct solvothermal methodology. The catalysts' structure and properties were studied and confirmed through various characterization techniques. The study showed that the catalysts' structure and properties were influenced by the molar ratio of tungstate, and they exhibited excellent acidic properties. Furthermore, the acidic properties of the catalysts were successfully utilized for the synthesis of indole derivatives, and the catalysts demonstrated high efficiency and reusability through multiple cycles.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Organic
Jianfeng Li, Xiaoting Wang, Rong-Ping Zhang, Lei Chen
Summary: Scalable syntheses of piceatannol-3'-O-beta-d-glucopyranoside and its 4'-methoxy counterpart were achieved using a route that includes early implemented Fischer-like glycosylation reaction, regioselective iodination of phenolic glycoside under strongly acidic conditions, highly telescoped route to access the styrene derivative, and key Mizoroki-Heck reaction for high overall yield of desired products.
SYNTHESIS-STUTTGART
(2022)
Article
Chemistry, Multidisciplinary
Kalyan Dey, Narayanaswamy Jayaraman
Summary: This study discloses a method for site-specific deprotonation, followed by alkylations and acylations of sugar hemiacetals to form the corresponding alkyl glycosides and acylated sugars in aqueous solutions. Pyridoneimine, a new base, is developed as a mediator for the deprotonation of readily available sugar hemiacetals and their subsequent reactions with alkylating and acylating agents.
CHEMICAL COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Irene Dini, Dario Tuccillo, Daniele Coppola, Margherita-Gabriella De Biasi, Elena Morelli, Andrea Mancusi
Summary: Fermentable sugar dosage is crucial for oenologists to determine the harvest time and control the fermentation process. Using automated instrumental analysis improves precision, reduces human errors, and saves time and cost. This study validated an enzymatic apparatus that can accurately measure glucose and fructose levels in wine samples, concluding that it is suitable for use in the industry.
Article
Chemistry, Physical
Anqi Ni, Danni Fu, Peng Lin, Xuemin Wang, Youyi Xia, Xinya Han, Tingting Zhang
Summary: In this study, a photothermal hydrogel evaporator incorporating eco-friendly poly(vinyl alcohol), agarose, Fe3+, and tannic acid (TA) was developed. The tannic acid-ferric ion (TA*Fe3+) complexes in the hydrogel exhibited excellent gelatinization and light-absorption properties. The hydrogel evaporator achieved a high interfacial evaporation rate of 1.897 ± 0.11 kg·m-2·h-1 with an energy efficiency of 89.7 ± 2.73%. Furthermore, the hydrogel demonstrated stability and maintained its evaporation performance in long-term tests and outdoor applications for wastewater treatment and seawater desalination.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Applied
Rafaela F. Cotta, Rafael A. Martins, Kelly A. da Silva Rocha, Elena F. Kozhevnikova, Ivan Kozhevnikov, Elena Gusevskaya
Summary: The acidic cesium salt of tungstophosphoric heteropoly acid was found to be an excellent solid acid catalyst for the reaction between phenylacetaldehyde and biorenewable monoterpenic alkenes, resulting in new products with high yields and sustainability.
Article
Green & Sustainable Science & Technology
Sergio S. de Jesus, Rubens Maciel Filho
Summary: Ionic liquids are molten salts with excellent chemical and thermal stability, which have the potential to replace traditional organic solvents. However, their synthesis, toxicity, and biodegradability pose challenges to their environmentally friendly use. Analyzing the processes of synthesis, recovery and recycling, toxicity, and biodegradability reveals the need for further improvements in ionic liquid design to meet the principles of green chemistry.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2022)
Article
Chemistry, Multidisciplinary
Jessica Jung, Lars Kaiser, Hans-Peter Deigner, Magnus S. Schmidt
Summary: In this study, bromoalkyl glycosides were successfully synthesized in microreactor scale by Fischer glycosylation, achieving yields between 24% and 40% after purification using various acidic catalysts and conditions. Some experiments demonstrated yields 180% higher than with previously known methods. Additionally, reversed-phase flash chromatography was shown to be more successful for purification, and longer bromoalcohols were found to be more compatible under these reaction conditions.
JOURNAL OF FLOW CHEMISTRY
(2022)
Article
Agriculture, Multidisciplinary
Fangping Zhong, Qi Zhang, Kejia Chen, Shichao Lan, Wenchao Yang, Xiuhai Gan
Summary: Natural products are important sources for the development of new eco-friendly antiviral agents. A cinnamic acid derivative containing a glycoside scaffold (compound 8d) exhibited strong antiviral activity against tobacco mosaic virus and tomato spotted wilt virus, and increased defense enzyme activities. Proteomic and transcriptome analyses revealed that compound 8d regulated gene transcription and protein expression levels involved in the defense response against virus infection. This study suggests that compound 8d is a promising lead candidate for the development of novel, eco-friendly, and natural-product-based antiviral agents.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Soo Young Cho, Dong Hae Ho, Yoon Young Choi, Soomook Lim, Sungjoo Lee, Ji Won Suk, Sae Byeok Jo, Jeong Ho Cho
Summary: Recent advances in metal additive manufacturing have provided new opportunities for prompt designs of prototypes and facile personalization of products. This study demonstrates a water-based solid-phase binding agent suitable for binder jetting 3D printing of metals, enabling elaborate 3D printing of metals with improved strengths and reducing the porosity between metal particles.
NATURE COMMUNICATIONS
(2022)
