Article
Biochemistry & Molecular Biology
Teja Ram, Ankit Kumar Singh, Prateek Pathak, Adarsh Kumar, Harshwardhan Singh, Maria Grishina, Jurica Novak, Pradeep Kumar
Summary: MEK mutations are common in various types of cancer, and the design of compounds with structural resemblance to FDA-approved MEK inhibitors has shown promise. Through chemical synthesis and computational studies, compound S15 was found to be the most potent against cancer cells, while compounds S1 and S5 were comparable to the standard drug trametinib.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Multidisciplinary
Seiji Ogo, Takeshi Yatabe, Tamon Tome, Riko Takenaka, Yoshihito Shiota, Kenji Kato
Summary: This paper reports a method for the synthesis of H2O2 using a homogeneous catalyst in water, using only H2 and O2 without flammable mixtures or cocatalysts. The catalyst can remove electrons from H2, store them for the reduction of O2, and allow the protonation of the reduced oxygen to form H2O2. The turnover number (TON) is 910 under an H2/O2 (95/5) atmosphere (1.9 MPa) for 12 hours at 23 degrees C, which is the highest among any homogeneous catalysts. Furthermore, a reaction mechanism based on two crystal structures is proposed.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Seiji Ogo, Takeshi Yatabe, Tamon Tome, Riko Takenaka, Yoshihito Shiota, Kenji Kato
Summary: In this study, a homogeneous catalyst is used to synthesize hydrogen peroxide using H2 and O2 in water, eliminating the need for flammable H2/O2 mixtures and cocatalysts. The catalyst is capable of extracting electrons from H2, storing them for the reduction of O2, and then converting the reduced oxygen to H2O2. The catalyst exhibits the highest turnover number (TON) among all homogeneous catalysts.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Agriculture, Multidisciplinary
Jia-Jie Hu, Duo Liu, Min-Zheng Cai, Yang Zhou, Wei-Xiao Yin, Chao-Xi Luo
Summary: In this study, a rapid one-pot RPA-CRISPR/Cas12 platform was established for the detection of benzimidazole resistance in Venturia carpophila. This method has the advantages of simplicity, rapidity, high sensitivity, high specificity, and ease of operation without the need for precision instruments and the need to isolate and culture pathogens. It can be used for monitoring resistant populations in fields and providing guidance on suitable management strategies for peach scab.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Materials Science, Ceramics
Enlei Zhang, Rui Xu, Lijie Wang, Jiaojiao Chen, Bengui Zhang, Guosheng Wang
Summary: This work focuses on the hydrogen production from sodium borohydride (NaBH4) hydrolysis using homogeneous copper ferrite (CuFe2O4) nanocubes. The nanocubes, produced without the use of surfactants, exhibited good catalytic activity and recyclability in the hydrolysis process. The hydrogen production rate reached up to 1.5 L/min/g at 303K, which is significantly higher than other CuFe2O4 materials. The effects of NaOH concentration, NaBH4 concentration, and reaction temperature were investigated, and the nanocubes were found to have a low activation energy of 41.53 kJ/mol.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Organic
Yuanyun Gu, Yan-En Wang, Yaqi Yuan, Haodong Xu, Yizhou Lu, Yufei Zhang, Fei Xue, Dan Xiong, Jianyou Mao
Summary: The deprotonation of allylbenzene was achieved using a catalytic alkali amide base, and the resulting allyl anion was trapped by N-(trimethylsilyl) aldimines to synthesize homoallylic amines. This one-pot method provided value-added products with excellent selectivity without the need for protection groups on the imines.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Applied
Jalal Rahmatinejad, Xudong Liu, Ximeng Zhang, Bahareh Raisi, Zhibin Ye
Summary: This study presents a method for synthesizing anode materials for sodium-ion batteries with high specific capacity, cyclic stability, and rate performance. The synthesized nanocomposite MoSx@HPC demonstrates superior performance compared to MoS2@HPC, indicating the advantageous role of amorphous MoSx.
JOURNAL OF ENERGY CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yi-Hsuan Lin, Shota Nishikawa, Tony Z. Jia, Fang-I. Yeh, Anna Khusnutdinova, Alexander F. Yakunin, Kosuke Fujishima, Po-Hsiang Wang
Summary: Phosphate is an essential ingredient in fertilizers and detergents, but it is a finite resource that may be exhausted within 70 years. Improper waste disposal can lead to eutrophication. Biological phosphorus removal is a sustainable method to recover and prevent ecosystem damage. Additionally, polyphosphates have various biological functions and biomedical applications, but efficient synthesis and application methods were lacking before this study.
Article
Polymer Science
Zishan Li, Jing Lyu, Yinghao Li, Bei Qiu, Melissa Johnson, Hongyun Tai, Wenxin Wang
Summary: Well-defined polyacrylamide (PAM) was successfully synthesized via a one-pot and one-step aqueous Cu(0)-mediated reversible-deactivation radical polymerization (RDRP). Strong deactivation control is the key to the controllability of acrylamide (AM) RDRPs, which depends on the equilibria of polymerization and mutual conversion of different copper species. Using this kinetically controlled strategy, PAMs with narrow molecular weight distributions (MWDs) and varied molecular weights (M(w)s) were achieved.
Article
Chemistry, Physical
Ningfang Zhou, Gang Luo, Wei Qin, Chun Wu, Chuankun Jia
Summary: A composite of boron-doped cobalt oxide nanorods coupled with reduced graphene oxide was synthesized by a one-step hydrothermal method, and its electrochemical performance for sodium ion storage was investigated. The results showed that boron doping and the introduction of graphene can improve the cycling stability and storage capacity of the electrode material. Therefore, the doping of boron and introduction of graphene have promising potential in optimizing the electrochemical performance of anode materials.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Review
Engineering, Chemical
Yamin Chai, Yanjia Zhang, Lichun Wang, Yunzheng Du, Biao Wang, Nan Li, Mengya Chen, Lailiang Ou
Summary: In this study, a three-dimensional MOF/hydrogel beads were successfully constructed with excellent mechanical performance and adsorption capacity, offering a promising strategy for high-efficiency wastewater treatment, especially in pharmaceutical wastewater treatment.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Jingyi Wang, Jianrui Feng, Yuying Li, Feili Lai, Gui-Chang Wang, Tianxi Liu, Jiajia Huang, Guanjie He
Summary: In this study, a novel structure of self-supported electrocatalyst Co-ALMO@NF was synthesized using a hydrothermal method. The Co-ALMO@NF exhibited excellent electrocatalytic performances, requiring low voltage and achieving high current density. The structural design of self-supported electrocatalysts was highlighted as important.
Article
Chemistry, Organic
Satyanarayana Tummanapalli, Shiva Kumar Punna, Kali Charan Gulipalli, Srinivas Endoori, Srinu Bodige, Anil Kumar Pommidi, Srinivas Medaboina, Suresh Choppadandi, Ravi Boya, Vijay Kumar Ganapathi, Devender Yadav Mamindla, Ramesh Konakalla, Gopala Krishna Bodala, Mahendar Reddy Bakangari, Sainath Dharmavaram Kottam, Dilip Jarikote, Taterao Potewar, Muralikrishna Valluri
Summary: A facile one-pot transformation method for the synthesis of chromone-2-carboxylate scaffold from 2-fluoroacetophenone has been developed, allowing chemists to start from different raw materials and maintain regioselectivity. The utility of this method has been demonstrated in the synthesis of natural products, bis-chromones, and potent anti-Alzheimer compounds, showing promising potential for finding new bioactive chromones with diverse modifications.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Green & Sustainable Science & Technology
Q. Yang, X. Ma, Y. Li, L. Jiang, D. Chen, J. He, J. Wang
Summary: Cu/Cu2O/biochar material was synthesized by a simple one-pot pyrolysis process, which showed great hydrophilic, good light absorption properties, and superior light-to-heat conversion efficiency, leading to enhanced solar water evaporation.
MATERIALS TODAY SUSTAINABILITY
(2023)
Article
Chemistry, Multidisciplinary
Emilija Milovic, Nenad Jankovic, Milan Vranes, Srdan Stefanovic, Jelena Petronijevic, Nenad Joksimovic, Jovana Muskinja, Zoran Ratkovic
Summary: This study presents a new synthetic method for the synthesis of pyrido-dipyrimidines in water, showcasing the advantages of green chemistry and high yields. The key intermediates of the reaction mechanism are enamine and vanillidene, contributing to the success of this one-pot heterocyclization approach.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
