Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation

Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse Model

(2014) Na Li et al.   CIRCULATION

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development

(2013) Julia O. Reynolds et al.   CARDIOVASCULAR RESEARCH

Enhanced Sarcoplasmic Reticulum Ca 2+ Leak and Increased Na + -Ca 2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation

(2012) Niels Voigt et al.   CIRCULATION

The PP1 binding code: a molecular-lego strategy that governs specificity

(2012) Ewald Heroes et al.   FEBS Journal

Inhibition of CaMKII Phosphorylation of RyR2 Prevents Induction of Atrial Fibrillation in FKBP12.6 Knockout Mice

(2011) Na Li et al.   CIRCULATION RESEARCH

Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice

(2011) Paulus Kirchhof et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Recent advances in the molecular pathophysiology of atrial fibrillation

(2011) Reza Wakili et al.   JOURNAL OF CLINICAL INVESTIGATION

CaMKII-Dependent Diastolic SR Ca 2+ Leak and Elevated Diastolic Ca 2+ Levels in Right Atrial Myocardium of Patients With Atrial Fibrillation

(2010) Stefan Neef et al.   CIRCULATION RESEARCH

New antiarrhythmic drugs for treatment of atrial fibrillation

(2010) Dobromir Dobrev et al.   LANCET

miR-1 Overexpression Enhances Ca 2+ Release and Promotes Cardiac Arrhythmogenesis by Targeting PP2A Regulatory Subunit B56α and Causing CaMKII-Dependent Hyperphosphorylation of RyR2

(2009) Dmitry Terentyev et al.   CIRCULATION RESEARCH

Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes

(2008) Sabine Huke et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural and Functional Characterization of Ryanodine Receptor-Natrin Toxin Interaction

(2008) Qiang Zhou et al.   BIOPHYSICAL JOURNAL

Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy

(2008) Ali El-Armouche et al.   CARDIOVASCULAR RESEARCH

Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation

(2008) Subeena Sood et al.   HEART RHYTHM