Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy

The HCM-Associated Cardiac Troponin T Mutation K280N Increases the Energetic Cost of Tension Generation in Human Cardiac Myofibrils

(2013) Claudia Ferrara et al.   BIOPHYSICAL JOURNAL

Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

(2013) Vasco Sequeira et al.   CIRCULATION RESEARCH

Transgenic Mouse α- and β-Cardiac Myosins Containing the R403Q Mutation Show Isoform-dependent Transient Kinetic Differences

(2013) Susan Lowey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy

(2012) Raffaele Coppini et al.   CIRCULATION

Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function

(2011) Sabine J. van Dijk et al.   Circulation-Heart Failure

Oxidation of Myofibrillar Proteins in Human Heart Failure

(2011) Marcella Canton et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Microvascular Function Is Selectively Impaired in Patients With Hypertrophic Cardiomyopathy and Sarcomere Myofilament Gene Mutations

(2011) Iacopo Olivotto et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Early identification of mutation carriers in familial hypertrophic cardiomyopathy by combined echocardiography and tissue Doppler imaging

(2010) Estelle Gandjbakhch et al.   EUROPEAN HEART JOURNAL

Prevalence and spectrum of mutations in a cohort of 192 unrelated patients with hypertrophic cardiomyopathy

(2010) Gilles Millat et al.   European Journal of Medical Genetics

Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy

(2010) Anita C. Hoskins et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients

(2010) Sabine J. van Dijk et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Cardiac Myosin-Binding Protein C Mutations and Hypertrophic Cardiomyopathy

(2009) Sabine J. van Dijk et al.   CIRCULATION

Evidence From Human Myectomy Samples That MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy Through Haploinsufficiency

(2009) Steven Marston et al.   CIRCULATION RESEARCH

Echocardiographic Strain Imaging to Assess Early and Late Consequences of Sarcomere Mutations in Hypertrophic Cardiomyopathy

(2009) Carolyn Y. Ho et al.   Circulation-Cardiovascular Genetics

Progress With Genetic Cardiomyopathies

(2009) Ray E. Hershberger et al.   Circulation-Heart Failure

Distinct myocardial effects of beta-blocker therapy in heart failure with normal and reduced left ventricular ejection fraction

(2009) Nazha Hamdani et al.   EUROPEAN HEART JOURNAL

Diastolic Abnormalities as the First Feature of Hypertrophic Cardiomyopathy in Dutch Myosin-Binding Protein C Founder Mutations

(2009) Michelle Michels et al.   JACC-Cardiovascular Imaging

Functional Effects of the Hypertrophic Cardiomyopathy R403Q Mutation Are Different in an α- or β-Myosin Heavy Chain Backbone

(2008) Susan Lowey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The familial hypertrophic cardiomyopathy-associated myosin mutation R403Q accelerates tension generation and relaxation of human cardiac myofibrils

(2008) Alexandra Belus et al.   JOURNAL OF PHYSIOLOGY-LONDON