The p65 subunit of NF-κB binds to PGC-1α, linking inflammation and metabolic disturbances in cardiac cells

The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

(2008) John J. Lehman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TNFα-antagonist neither improve cardiac remodelling or cardiac function at early stage of heart failure in diabetic rats

(2008) Azra Isic et al.   AUTOIMMUNITY

TNF-α reduces PGC-1α expression through NF-κB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model

(2008) Xavier Palomer et al.   CARDIOVASCULAR RESEARCH

Transcriptional control of mitochondrial biogenesis: the central role of PGC-1 

(2008) R. Ventura-Clapier et al.   CARDIOVASCULAR RESEARCH

SCFCdc4 acts antagonistically to the PGC-1  transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis

(2008) B. L. Olson et al.   GENES & DEVELOPMENT

Antagonism of E2F-1 regulated Bnip3 transcription by NF- B is essential for basal cell survival

(2008) J. Shaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy

(2007) Guixiang Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Prevention of Cardiac Hypertrophy and Heart Failure by Silencing of NF-κB

(2007) Sudhiranjan Gupta et al.   JOURNAL OF MOLECULAR BIOLOGY

The PPARα-PGC-1αAxis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium

(2007) Jennifer G. Duncan et al.   PPAR Research