Aliskiren and Valsartan Reduce Myocardial AT1 Receptor Expression and Limit Myocardial Infarct Size in Diabetic Mice

AKT signalling in the failing heart

(2011) Antoine H. Chaanine et al.   EUROPEAN JOURNAL OF HEART FAILURE

Handle Region Peptide Counteracts the Beneficial Effects of the Renin Inhibitor Aliskiren in Spontaneously Hypertensive Rats

(2011) Joep H.M. van Esch et al.   HYPERTENSION

The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy

(2011) N. R. Sundaresan et al.   Science Signaling

The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA

(2010) Yumei Ye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Cardioprotection with Postconditioning: Loss of Efficacy in Murine Models of Type-2 and Type-1 Diabetes

(2010) Karin Przyklenk et al.   ANTIOXIDANTS & REDOX SIGNALING

Diabetes mellitus abrogates erythropoietin-induced cardioprotection against ischemic-reperfusion injury by alteration of the RISK/GSK-3β signaling

(2010) Nehmat Ghaboura et al.   BASIC RESEARCH IN CARDIOLOGY

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

(2010) Derek J. Hausenloy et al.   BASIC RESEARCH IN CARDIOLOGY

Additive Effect of TAK-491, a New Angiotensin Receptor Blocker, and Pioglitazone, in Reducing Myocardial Infarct Size

(2010) Yumei Ye et al.   CARDIOVASCULAR DRUGS AND THERAPY

Cyclosporine A at Reperfusion Reduces Infarct Size in Pigs

(2010) Andreas Skyschally et al.   CARDIOVASCULAR DRUGS AND THERAPY

Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion

(2010) Chiao-Po Hsu et al.   CIRCULATION

Aliskiren

(2010) Sean T. Duggan et al.   DRUGS

Beneficial cardiac effects of the renin inhibitor aliskiren in spontaneously hypertensive rats

(2010) Joep HM van Esch et al.   JOURNAL OF HYPERTENSION

Renin inhibition mitigates anti-angiogenesis in spontaneously hypertensive rats

(2010) Krisztina Rusai et al.   JOURNAL OF HYPERTENSION

Transient upregulation of PGC-1α diminishes cardiac ischemia tolerance via upregulation of ANT1

(2010) Edward G. Lynn et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1α Expression in experimental stroke

(2010) Hai-rong Zhu et al.   NEUROPHARMACOLOGY

Role of angiotensin II and oxidative stress in vascular insulin resistance linked to hypertension

(2009) Ming-Sheng Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Protective Role of SIRT1 in Diabetic Vascular Dysfunction

(2009) Masayuki Orimo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Valsartan regulates the interaction of angiotensin II type 1 receptor and endothelial nitric oxide synthase via Src/PI3K/Akt signalling

(2009) Kuo-Hui Su et al.   CARDIOVASCULAR RESEARCH

Short Communication: Angiotensin II Type 1 Receptor–Mediated Upregulation of Calcineurin Activity Underlies Impairment of Cardioprotective Signaling in Diabetic Hearts

(2009) Hiroyuki Hotta et al.   CIRCULATION RESEARCH

Direct Renin Inhibition Improves Systemic Insulin Resistance and Skeletal Muscle Glucose Transport in a Transgenic Rodent Model of Tissue Renin Overexpression

(2009) Guido Lastra et al.   ENDOCRINOLOGY

Intra-coronary administration of cyclosporine limits infarct size, attenuates remodeling and preserves left ventricular function in porcine acute anterior infarction

(2009) Jiunn-Jye Sheu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD

(2009) Ramon Amat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Valsartan preconditioning protects against myocardial ischemia–reperfusion injury through TLR4/NF-κB signaling pathway

(2009) Jian Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway

(2009) D. Della-Morte et al.   NEUROSCIENCE

Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart

(2008) Seiji Matsuhisa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The role of eNOS, iNOS, and NF-κB in upregulation and activation of cyclooxygenase-2 and infarct size reduction by atorvastatin

(2008) Yumei Ye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

N-Acetylcysteine Abolishes the Protective Effect of Losartan Against Left Ventricular Remodeling in Cardiomyopathy Hamster

(2008) Seiji Matsuhisa et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells

(2008) Ryohei Miyazaki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cardioprotection

(2008) Gerd Heusch et al.   CIRCULATION

Ischemic Postconditioning in Pigs

(2008) Andreas Skyschally et al.   CIRCULATION RESEARCH

Renin Inhibition Attenuates Insulin Resistance, Oxidative Stress, and Pancreatic Remodeling in the Transgenic Ren2 Rat

(2008) Javad Habibi et al.   ENDOCRINOLOGY

Renin Inhibitor Aliskiren Improves Impaired Nitric Oxide Bioavailability and Protects Against Atherosclerotic Changes

(2008) Toshio Imanishi et al.   HYPERTENSION

Renin Inhibition Improves Cardiac Function and Remodeling After Myocardial Infarction Independent of Blood Pressure

(2008) Dirk Westermann et al.   HYPERTENSION

Renin-angiotensin system revisited

(2008) F. Fyhrquist et al.   JOURNAL OF INTERNAL MEDICINE

Direct renin inhibition: clinical pharmacology

(2008) Michel Azizi   JOURNAL OF MOLECULAR MEDICINE-JMM

Renin inhibition and atherosclerosis

(2008) F. C. Luft   NEPHROLOGY DIALYSIS TRANSPLANTATION