ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion

RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response

(2012) Jiping Wang et al.   Cardiovascular Diabetology

High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels

(2012) Taiga Ichinomiya et al.   Cardiovascular Diabetology

A Novel RhoA/ROCK-CPI-17-MEF2C Signaling Pathway Regulates Vascular Smooth Muscle Cell Gene Expression

(2012) Christina Pagiatakis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1–9) axis in experimental hypertension

(2011) María P Ocaranza et al.   JOURNAL OF HYPERTENSION

Can protein biomarkers provide an index of coronary artery calcification in patients with Type 2 diabetes?

(2010) I.F. Godsland et al.   ATHEROSCLEROSIS

Pitavastatin decreases the expression of endothelial lipase both in vitro and in vivo

(2010) Y. Kojima et al.   CARDIOVASCULAR RESEARCH

Activation of the ROCK1 Branch of the Transforming Growth Factor-β Pathway Contributes to RAGE-Dependent Acceleration of Atherosclerosis in Diabetic ApoE-Null Mice

(2010) De-xiu Bu et al.   CIRCULATION RESEARCH

HYPERGLYCEMIA INDUCED CELL GROWTH AND GENE EXPRESSION VIA THE SERUM RESPONSE ELEMENT THROUGH RhoA AND Rho-KINASE IN VASCULAR SMOOTH MUSCLE CELLS

(2010) Kai Ishiko et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Effects of fasudil on early atherosclerotic plaque formation and established lesion progression in apolipoprotein E-knockout mice

(2009) Duo-Jiao Wu et al.   ATHEROSCLEROSIS

Molecular Insights and Therapeutic Targets for Diabetic Endothelial Dysfunction

(2009) Jian Xu et al.   CIRCULATION

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

(2009) D. Yao et al.   DIABETES

Association Between Plasma Monocyte Chemoattractant Protein-1 Concentration and Cardiovascular Disease Mortality in Middle-Aged Diabetic and Nondiabetic Individuals

(2009) L. Piemonti et al.   DIABETES CARE

Statins inhibit Rho kinase activity in patients with atherosclerosis

(2008) Anju Nohria et al.   ATHEROSCLEROSIS

Endothelial Dysfunction in Diabetes: From Mechanisms to Therapeutic Targets

(2008) Maria Potenza et al.   CURRENT MEDICINAL CHEMISTRY

Applications for ROCK kinase inhibition

(2008) Michael F Olson   CURRENT OPINION IN CELL BIOLOGY

Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage

(2008) R. Arita et al.   DIABETES

ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury

(2008) Kensuke Noma et al.   JOURNAL OF CLINICAL INVESTIGATION

Soluble ICAM-1 and VCAM-1 as Markers of Endothelial Activation

(2008) V. Videm et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and their association with clinical outcome, troponin T and C-reactive protein in patients with acute coronary syndromes

(2007) Arman S. Postadzhiyan et al.   CLINICAL BIOCHEMISTRY