Article
Endocrinology & Metabolism
Bang Zheng, Bowen Su, Geraint Price, Ioanna Tzoulaki, Sara Ahmadi-Abhari, Lefkos Middleton
Summary: Type 2 diabetes is a known risk factor for dementia, with higher or unstable HbA(1c) levels and the presence of diabetic complications increasing the risk of dementia among patients with diabetes. Effective management of glycemia may play a significant role in preserving cognitive health in older adults with diabetes.
Article
Endocrinology & Metabolism
Joseph E. O'Reilly, Anita Jeyam, Thomas M. Caparrotta, Joseph Mellor, Andreas Hohn, Paul M. McKeigue, Stuart J. McGurnaghan, Luke A. K. Blackbourn, Rory McCrimmon, Sarah H. Wild, John R. Petrie, John A. McKnight, Brian Kennon, John Chalmers, Sam Phillip, Graham Leese, Robert S. Lindsay, Naveed Sattar, Fraser W. Gibb, Helen M. Colhoun
Summary: The study found that the incidence of DKA among individuals with type 1 diabetes in Scotland has increased since 2004, except in the 10-19 age group. There are strong and widening socioeconomic disparities in DKA outcomes, indicating a need for efforts to prevent DKA in vulnerable groups.
Article
Endocrinology & Metabolism
Jie Yu, Yiwen Liu, Lu Lyu, Yuan Zhao, Mengya Qi, Fan Ping, Lingling Xu, Wei Li, Qiang Xu, Huabing Zhang, Wenming Wu, Yuxiu Li
Summary: New and optimized diagnostic criteria for endogenous hyperinsulinemic hypoglycemia in the Chinese population have been proposed, and these criteria yield satisfactory accuracy.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Food Science & Technology
Zifeng Huang, Jie Chen, Chang 'e Wang, Meifang Xiao, Yuxian Zhu, Na Li, Zirui Huang, Bin Liu, Ying Huang
Summary: This study aimed to investigate the hypoglycemic effect of Chlorella pyrenoidosa functional formulations (CFF) on STZ-induced high-glucose and high-fat diet-fed mice. CFF significantly reduced weight loss, liver deformation, cecum injury, and jejunal inflammation in type 2 diabetic mice. In addition, CFF enriched gut probiotics, inhibited harmful microorganisms, and enhanced production of short-chain fatty acids.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Endocrinology & Metabolism
Roque Cardona-Hernandez, Anke Schwandt, Hessa Alkandari, Heiko Bratke, Agata Chobot, Nicole Coles, Sarah Corathers, Damla Goksen, Peter Goss, Zineb Imane, Katrin Nagl, Stephen M. P. O'Riordan, Craig Jefferies
Summary: Insulin delivery methods, glucose-monitoring modalities, and related outcomes were examined in a large, international cohort of children and adolescents with type 1 diabetes from the SWEET-Registry. Participants using pumps or continuous glucose monitoring showed lower HbA(1c) and fewer DKA episodes, with pump use associated with a lower rate of severe hypoglycemia. The concomitant use of pump and CGM showed an additive benefit in improving outcomes.
Article
Medicine, Research & Experimental
Pengpeng Zhang, Wei Wei, Xiaohai Zhang, Chaoling Wen, Chitchamai Ovatlarnporn, Opeyemi Joshua Olatunji
Summary: This study found that the ethanolic extract of Krat has significant antidiabetic and antihyperlipidemic effects on type 2 diabetic rats. These results for the first time demonstrated the potential of Mitragyna speciosa in the treatment of diabetes and provide scientific reinforcement for its traditional use.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Endocrinology & Metabolism
Niala den Braber, Miriam M. R. Vollenbroek-Hutten, Kathryn M. Westerik, Stephan J. L. Bakker, Gerjan Navis, Bert-Jan F. van Beijnum, Gozewijn D. Laverman
Summary: In insulin-treated patients with type 2 diabetes, high HbA(1c) did not decrease the occurrence of nocturnal hypoglycemia, and low HbA(1c) was not associated with the highest time in range (TIR). Optimal personalization of glycemic control requires the use of newer tools, including CGM-derived parameters.
Article
Urology & Nephrology
Cristina Martin-Higueras, Sander F. Garrelfs, Jaap W. Groothoff, Dorrit E. Jacob, Shabbir H. Moochhala, Justine Bacchetta, Cecile Acquaviva, Marcin Zaniew, Przymyslaw Sikora, Bodo B. Beck, Bernd Hoppe
Summary: Outcome data for primary hyperoxaluria type 3 (PH3), considered a milder form of PH with lower risk of chronic kidney disease, are scarce. A retrospective analysis of the largest PH3 cohort to date revealed that PH3 is more similar to PH1 and PH2 than previously thought, presenting as early-onset, recurrent stone disease with potential kidney impairment.
KIDNEY INTERNATIONAL
(2021)
Article
Polymer Science
Jian-Miao Yang, Lin-Jie Wu, Meng-Ting Lin, Yi-Ying Lu, Tian-Tian Wang, Min Han, Bin Zhang, Dong-Hang Xu
Summary: In this study, chitosan-based nanocarriers were developed to enhance the oral delivery of therapeutic peptides. The chitosan/alginate nanoparticles demonstrated efficient cellular uptake, controlled release, and protection against enzymatic degradation, leading to improved oral absorption and stability.
Article
Pharmacology & Pharmacy
Ilaria Campesi, Giuseppe Seghieri, Flavia Franconi
Summary: Numerous pieces of evidence suggest that women with diabetes have a greater excess risk of cardiovascular diseases than men, and they are at a disadvantage in terms of metabolic control and treatment efficacy. Both old and new glucose-lowering drugs show some sex-and-gender differences, and there is under-representation of women in cardiovascular outcome trials. Pharmacology research should consider gender perspectives to bridge these gender gaps.
CURRENT OPINION IN PHARMACOLOGY
(2021)
Article
Medicine, General & Internal
Katharina Warncke, Alexander Eckert, Ezio Bonifacio, Peter Achenbach, Olga Kordonouri, Thomas Meissner, Ute Ohlenschlaeger, Walter Bonfig, Anette-G. Ziegler, Reinhard W. Holl
Summary: This study aimed to determine whether subgroups of childhood diabetes are associated with diabetes-specific complications and could be a basis for personalised therapies. The researchers found that subgrouping of childhood diabetes at diagnosis could provide prognostic value for the development of acute and chronic diabetes-specific complications.
Article
Biochemistry & Molecular Biology
Yongli Zhang, Tao Wu, Wen Li, Yunjiao Zhao, Hairong Long, Rui Liu, Wenjie Sui, Min Zhang
Summary: Lactobacillus casei LC89 demonstrates anti-diabetic effects in T2DM mice by regulating blood glucose levels, improving insulin resistance, and reducing inflammation through modulation of gut microbiota and glucagon signal pathway related genes.
Article
Biochemistry & Molecular Biology
Junyu Hao, Yongli Zhang, Tao Wu, Rui Liu, Wenjie Sui, Jianguo Zhu, Shuguang Fang, Jieting Geng, Min Zhang
Summary: BL21 supplementation was found to significantly reduce blood glucose levels and alleviate insulin resistance, enhance anti-oxidative capacity, increase hepatic glycogen content, and regulate gene expression related to glucose metabolism. Additionally, BL21 improved endotoxemia-related inflammation and impaired intestinal barrier function in diabetic mice, while also modulating the composition of gut microbiota.
Article
Food Science & Technology
Najme Oliyaei, Marzieh Moosavi-Nasab, Ali Mohammad Tamaddon, Nader Tanideh
Summary: Encapsulated fucoxanthin with porous starch showed significant antidiabetic effects in diabetic mice, as evidenced by reduced weight gain, improved blood glucose and insulin levels, and lowered cholesterol and triglyceride levels. The study also demonstrated a potential regeneration of pancreatic beta cells with the administration of fucoxanthin, indicating its potential as a bioactive compound for natural diabetes therapy.
FOOD SCIENCE & NUTRITION
(2021)
Article
Neurosciences
Frederik Norregaard Pedersen, Lonny Stokholm, Frans Pouwer, Katrine Hass Rubin, Tunde Peto, Ulrik Frydkjaer-Olsen, Anne Suhr Thykjaer, Nis Andersen, Jens Andresen, Toke Bek, Morten La Cour, Steffen Heegaard, Kurt Hojlund, Ryo Kawasaki, Javad Nouri Hajari, Kirsten Ohm Kyvik, Caroline Schmidt Laugesen, Katja Christina Schielke, Rafael Simo, Jakob Grauslund
Summary: Individuals with diabetes without DR were less likely to develop AD compared to persons without diabetes. However, individuals with DR had a 34% higher risk of incident AD, which raise the question whether screening for cognitive impairment should be done among individuals with DR.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Endocrinology & Metabolism
Peter Bramlage, Stefanie Lanzinger, Wolfgang Rathmann, Anton Gillessen, Nikolaus Scheper, Sebastian M. Schmid, Matthias Kaltheuner, Jochen Seufert, Thomas Danne, Reinhard W. Holl
DIABETES OBESITY & METABOLISM
(2017)
Article
Cardiac & Cardiovascular Systems
Nikolaos Bonaros, Rainer Petzina, Riccardo Cocchieri, Dariusz Jagielak, Marco Aiello, Joel Lapeze, Mika Laine, Sidney Chocron, Douglas Muir, Walter Eichinger, Matthias Thielmann, Louis Labrousse, Vinayak Bapat, Kjell Arne Rein, Jean-Philippe Verhoye, Gino Gerosa, Hardy Baumbach, Markus Kofler, Peter Bramlage, Cornelia Deutsch, Martin Thoenes, Derk Frank, Mauro Romano
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2017)
Correction
Cardiac & Cardiovascular Systems
Peter Bramlage, Stephanie L. Swift, Martin Thoenes, Joan Minguet, Carmen Ferrero, Roland E. Schmieder
EUROPEAN JOURNAL OF HEART FAILURE
(2017)
Correction
Pediatrics
Beate Beime, Cornelia Deutsch, Ralf Kruger, Andreas Wolf, Peter Mueller, Gertrud Hammel, Peter Bramlage
EUROPEAN JOURNAL OF PEDIATRICS
(2017)
Article
Pediatrics
Beate Beime, Cornelia Deutsch, Ralf Krueger, Andreas Wolf, Peter Mueller, Gertrud Hammel, Peter Bramlage
EUROPEAN JOURNAL OF PEDIATRICS
(2017)
Article
Cardiac & Cardiovascular Systems
P. Bramlage, W. Maerz, D. Westermann, B. Weisser, J. H. Wirtz, U. Zeymer, P. Baumgart, G. van Mark, U. Laufs, B. K. Kraemer, T. Unger
Article
Endocrinology & Metabolism
Jean Ferrieres, Dominik Lautsch, Anselm K. Gitt, Gaetano De Ferrari, Hermann Toplak, Moses Elisaf, Heinz Drexel, Martin Horack, Carl Baxter, Baishali Ambegaonkar, Philippe Brudi, Peter P. Toth
DIABETES OBESITY & METABOLISM
(2018)
Article
Medicine, General & Internal
Christian Butter, Jessica Gross, Anja Haase-Fielitz, Helen Sims, Cornelia Deutsch, Peter Bramlage, Michael Neuss
JOURNAL OF CLINICAL MEDICINE
(2018)
Article
Cardiac & Cardiovascular Systems
Jean Ferrieres, Dominik Lautsch, Peter Bramlage, Martin Horack, Carl A. Baxter, Baishali Ambegaonkar, Peter P. Toth, Kian-Keong Poh, Gaetano Maria De Ferrari, Anselm K. Gitt
ARCHIVES OF CARDIOVASCULAR DISEASES
(2020)
Article
Biochemistry & Molecular Biology
Thomas Kubin, Ayse Cetinkaya, Natalia Kubin, Peter Bramlage, Bedriye Sen-Hild, Praveen Gajawada, Hakan Akintuerk, Markus Schoenburg, Wolfgang Schaper, Yeong-Hoon Choi, Miroslav Barancik, Manfred Richter
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Medicine, General & Internal
Katja Bohmann, Christof Burgdorf, Tobias Zeus, Michael Joner, Hector Alvarez, Kira Lisanne Berning, Maren Schikowski, Albert Markus Kasel, Gesine van Mark, Cornelia Deutsch, Jana Kurucova, Martin Thoenes, Derk Frank, Steffen Wundram, Peter Bramlage, Barbara Miller, Verena Veulemans
Summary: Implementation of a dedicated TAVI coordinator program can improve pathway efficiency, enhance patient satisfaction, and optimize post-TAVI care.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Anselm K. Gitt, Ulrich Laufs, Winfried Marz, W. Dieter Paar, Peter Bramlage, Nikolaus Marx, Klaus G. Parhofer
Summary: This study provides insights into the clinical characteristics and current treatment status of patients with FH in Germany. Many patients with FH fail to achieve recommended lipid levels.
JOURNAL OF CLINICAL MEDICINE
(2022)
Letter
Peripheral Vascular Disease
Peter Bramlage, Stephan Lueders, Ulrich Tholl
BLOOD PRESSURE MONITORING
(2017)
Article
Cardiac & Cardiovascular Systems
Christian Ott, Agnes Jumar, Kristina Striepe, Stefanie Friedrich, Marina V. Karg, Peter Bramlage, Roland E. Schmieder
CARDIOVASCULAR DIABETOLOGY
(2017)
Article
Cardiac & Cardiovascular Systems
Norbert Frey, Richard P. Steeds, Antonio Serra, Eberhard Schulz, Stephan Baldus, Matthias Lutz, Christiane Pohlmann, Jana Kurucova, Peter Bramlage, David Messika-Zeitoun
BMC CARDIOVASCULAR DISORDERS
(2017)