Article
Medicine, General & Internal
Alexandre Bodin, Arnaud Bisson, Clementine Andre, Dominique Babuty, Nicolas Clementy
Summary: Pseudo MPP using intentional anodal capture with a quadripolar left ventricular lead, mimicking conventional multisite pacing, is feasible in most of CRT patients with comparable energy consumption. The theoretical longevity was 6.2 years for MPP, 5.6 years for pseudo-MPP, and 13.7 years for BVp. Further studies on their potential clinical impact are needed.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Ben B. Chung, Jonathan S. Grinstein, Teruhiko Imamura, Eric Kruse, Ann B. Nguyen, Nikhil Narang, Luise H. Holzhauser, Daniel Burkhoff, Roberto M. Lang, Gabriel T. Sayer, Nir Y. Uriel
Summary: In this prospective randomized study comparing RV vs BiV pacing in LVAD patients, RV pacing was associated with significantly improved functional status, quality of life, fewer ventricular tachyarrhythmias, and stable lead impedance compared with BiV pacing. This study supports turning off LV lead pacing in LVAD patients with CRT.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Yao Wang, Haojie Zhu, Xiaofeng Hou, Zhao Wang, Fengwei Zou, Zhiyong Qian, Yongyue Wei, Xiang Wang, Longyao Zhang, Xiaofei Li, Zhimin Liu, Siyuan Xue, Chaotong Qin, Jiaxin Zeng, Hui Li, Hongping Wu, Hong Ma, Kenneth A. Ellenbogen, Michael R. Gold, Xiaohan Fan, Jiangang Zou
Summary: Left bundle branch pacing (LBBP) shows greater improvement in left ventricular ejection fraction (LVEF) compared to biventricular pacing (BiVP) in heart failure patients with nonischemic cardiomyopathy and left bundle branch block (LBBB).
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Cameron Pfeffer, Michael Fryer, Jing Xian Quah, Naresh Dayananda, Matthew Tung
Summary: Our study analyzed cardiac electrograms to identify characteristics for detecting cathodal, anodal, or cathodal-anodal capture in left ventricular quadripolar pacing leads of cardiac resynchronization therapy patients, and examined the relationship between these characteristics and the electrocardiogram.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Wen Liu, Chunqiang Hu, Yanan Wang, Yufei Cheng, Yingjie Zhao, Yang Liu, Shaoxin Zheng, Haiyan Chen, Xianhong Shu
Summary: LBBAP effectively improves cardiac function, mechanical synchronization, and mechanical efficiency in heart failure patients, suggesting it as a promising alternative for cardiac resynchronization therapy compared to traditional BVP.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
John Rickard, Kevin Jackson, Michael Gold, Mauro Biffi, Matteo Ziacchi, Joshua Silverstein, Brian Ramza, Mark Metzl, Eric Grubman, Richard Abben, Niraj Varma, Ghiyath Tabbal, Cory Jensen, Griet Wouters, Subham Ghosh, Kevin Vernooy
Summary: This study aimed to evaluate the efficacy of the EBS in patients less likely to respond to CRT and determine whether it is superior to standard CRT care. The results showed no significant difference in left ventricular end-systolic volume improvement between patients with EBS and control patients, suggesting that EBS-guided therapy for CRT management of heart failure is not supported.
Article
Medicine, General & Internal
Patricia Zerlang Fruelund, Anders Sommer, Jens Brondum Frokjaer, Soren Lundbye-Christensen, Tomas Zaremba, Peter Sogaard, Claus Graff, Soren Vraa, Aksayan Arunanthy Mahalingasivam, Anna Margrethe Thogersen, Michael Rangel Pedersen, Sam Riahi
Summary: Prospective studies using fluoroscopy to assess right ventricular lead position have not shown clear benefits from septal pacing. This retrospective study investigated the impact of different RV lead positions on the risk of pacing-induced cardiomyopathy (PICM). The results showed a high risk of PICM regardless of lead position in patients with normal pre-implant left ventricular function.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Pugazhendhi Vijayaraman, Parikshit S. Sharma, Oscar Cano, Shunmuga Sundaram Ponnusamy, Bengt Herweg, Francesco Zanon, Marek Jastrzebski, Jiangang Zou, Mihail G. Chelu, Kevin Vernooy, Zachary I. Whinnett, Girish M. Nair, Manuel Molina-Lerma, Karol Curila, Dipen Zalavadia, Abdul Haseeb, Cicely Dye, Sharath C. Vipparthy, Ryan Brunetti, Pawel Moskal, Alexandra Ross, Antonius van Stipdonk, Jerin George, Yusuf K. Qadeer, Mishal Mumtaz, Jeffrey Kolominsky, Syeda A. Zahra, Mehrdad Golian, Lina Marcantoni, Faiz A. Subzposh, Kenneth A. Ellenbogen
Summary: This study compared the clinical outcomes between left bundle branch area pacing (LBBAP) and biventricular pacing (BVP) in patients with cardiac resynchronization therapy (CRT). The results showed that LBBAP improved clinical outcomes compared to BVP and may be a reasonable alternative.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Margarida Pujol-Lopez, Rafael Jimenez Arjona, Eduard Guasch, Roger Borras, Adelina Doltra, Sara Vazquez-Calvo, Ivo Roca-Luque, Paz Garre, Elisenda Ferro, Mireia Niebla, Esther Carro, Jose L. Puente, Laura Uribe, Eric Invers, Maria Angeles Castel, Elena Arbelo, Marta Sitges, Lluis Mont, Jose M. Tolosana
Summary: This study compared the echocardiographic response and clinical improvement between His-Purkinje conduction system pacing (HPCSP) and biventricular cardiac resynchronization therapy (BiVCRT) in patients with left ventricular dysfunction. The results showed that HPCSP improved left ventricular ejection fraction (LVEF) and induced a similar response to BiVCRT in patients with LVEF ≤ 45% and atrioventricular block. Additionally, HPCSP significantly improved mitral regurgitation and NYHA functional class.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Xiaofei Li, Junmeng Zhang, Chunguang Qiu, Zhao Wang, Hui Li, Kunjing Pang, Yan Yao, Zhimin Liu, Ruiqin Xie, Yangxin Chen, Yongquan Wu, Xiaohan Fan
Summary: Left bundle branch area pacing (LBBAP) may reduce the risk of heart failure hospitalization or upgrade to biventricular pacing compared to right ventricular pacing (RVP) in patients with atrioventricular block requiring a high burden of ventricular pacing. The difference in clinical outcomes between LBBAP and RVP was mainly observed in patients with high ventricular pacing burden or baseline lower LVEF levels. Independent predictors of the primary outcome included LBBAP, previous myocardial infarction, and baseline LVEF.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Physiology
Marina Strocchi, Nadeev Wijesuriya, Mark K. Elliott, Karli Gillette, Aurel Neic, Vishal Mehta, Edward J. Vigmond, Gernot Plank, Christopher A. Rinaldi, Steven A. Niederer
Summary: Biventricular endocardial pacing and left bundle pacing are new delivery methods for cardiac resynchronization therapy. Leadless pacing can be used to avoid risks associated with traditional lead systems. This study investigated the impact of RV-LV delay, RV lead location, and left bundle capture on the efficacy of leadless pacing.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Michael Vinther, Niels Risum, Jesper Hastrup Svendsen, Rasmus Mogelvang, Berit Thornvig Philbert
Summary: This study compared His-CRT and BiV-CRT in patients with symptomatic heart failure and LBBB, finding similar clinical and physical improvements in both groups at the 6-month follow-up, with His-CRT requiring higher pacing thresholds.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Shengjie Wu, Lan Su, Pugazhendhi Vijayaraman, Rujie Zheng, Mengxing Cai, Lei Xu, Ruiyu Shi, Zhouqing Huang, Zachary Whinnett, Weijian Huang
Summary: Left bundle branch pacing (LBBP) appears to be a promising method for delivering cardiac resynchronization therapy (CRT), showing similar improvements in symptoms and left ventricular function compared with His bundle pacing (HBP) but more significant than biventricular pacing (BVP).
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Jiyi Liu, Fengzhi Sun, Zefeng Wang, Jiao Sun, Xue Jiang, Weilong Zhao, Zhipeng Zhang, Lu Liu, Shulong Zhang
Summary: In patients with heart failure eligible for cardiac resynchronization therapy (CRT), left bundle branch area pacing (LBBAP) showed significant improvements in QRS duration, left ventricular ejection fraction, left ventricular end-diastolic dimension, New York Heart Association class, and CRT response compared to biventricular pacing (BVP). The current evidence from non-randomized studies suggests that LBBAP is a promising method for CRT, offering more remarkable improvements in symptoms and cardiac function.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Juan Carlos Diaz, William H. Sauer, Mauricio Duque, Bruce A. Koplan, Eric D. Braunstein, Jorge Eduardo Marin, Julian Aristizabal, Cesar Daniel Nino, Oriana Bastidas, Juan Manuel Martinez, Carolina Hoyos, Carlos D. Matos, Nestor Lopez-Cabanillas, Nathaniel A. Steiger, Sunil Kapur, Thomas M. Tadros, David T. Martin, Paul C. Zei, Usha B. Tedrow, Jorge E. Romero
Summary: This study compares the outcomes of LBBAP and BiVp as initial implant strategies for CRT. The results show that LBBAP as an initial CRT strategy can reduce the risk of hospitalization due to heart failure compared to BiVp, and improvements in procedural and fluoroscopy times, QRS duration, and left ventricular ejection fraction were observed.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)