Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma

Is Fibroblast Growth Factor Receptor 4 a Suitable Target of Cancer Therapy?

(2014) Christine Heinzle et al.   CURRENT PHARMACEUTICAL DESIGN

Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs

(2013) Chiara Francavilla et al.   MOLECULAR CELL

Blockade of Nonhormonal Fibroblast Growth Factors by FP-1039 Inhibits Growth of Multiple Types of Cancer

(2013) T. C. Harding et al.   Science Translational Medicine

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

A Novel Monoclonal Antibody to Fibroblast Growth Factor 2 Effectively Inhibits Growth of Hepatocellular Carcinoma Xenografts

(2012) L. Wang et al.   MOLECULAR CANCER THERAPEUTICS

Targeting Fibroblast Growth Factor Receptor Signaling in Hepatocellular Carcinoma

(2012) Ann-Lii Cheng et al.   ONCOLOGY

Targeting FGFR4 Inhibits Hepatocellular Carcinoma in Preclinical Mouse Models

(2012) Dorothy M. French et al.   PLoS One

Soluble FGFR4 extracellular domain inhibits FGF19-induced activation of FGFR4 signaling and prevents nonalcoholic fatty liver disease

(2011) Qiang Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

(2011) Eric T. Sawey et al.   CANCER CELL

Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy

(2011) Christine Heinzle et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Integrins Regulate Microtubule Nucleating Activity of Centrosome through Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase/Extracellular Signal-regulated Kinase (MEK/ERK) Signaling

(2011) Diane Colello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

(2011) Dontscho Kerjaschki et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): An emerging field for advanced technologies

(2011) Jens U. Marquardt et al.   JOURNAL OF HEPATOLOGY

Neural cell adhesion molecule differentially interacts with isoforms of the fibroblast growth factor receptor

(2011) Claus Christensen et al.   NEUROREPORT

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis

(2010) Christine Gauglhofer et al.   HEPATOLOGY

Hepatocellular Carcinoma (HCC)

(2010) Peter Ferenci et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Integrins and cell-fate determination

(2009) C. H. Streuli   JOURNAL OF CELL SCIENCE

New cellular tools reveal complex epithelial–mesenchymal interactions in hepatocarcinogenesis

(2008) S Sagmeister et al.   BRITISH JOURNAL OF CANCER

Integrins as regulators of the mitotic machinery

(2008) Susan E LaFlamme et al.   CURRENT OPINION IN CELL BIOLOGY

Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention

(2008) Han Kiat Ho et al.   JOURNAL OF HEPATOLOGY

Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition

(2008) Hendrik Fischer et al.   MOLECULAR CANCER THERAPEUTICS