SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

(2016) Ronald A. McCord et al.   Aging-US

Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy

(2012) Kristan E. van der Vos et al.   NATURE CELL BIOLOGY

Sirtuin 1 Is Upregulated in a Subset of Hepatocellular Carcinomas where It Is Essential for Telomere Maintenance and Tumor Cell Growth

(2011) J. Chen et al.   CANCER RESEARCH

The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

(2011) Bo Yang et al.   CELL CYCLE

Cellular and molecular effects of sirtuins in health and disease

(2011) Yoshiyuki Horio et al.   CLINICAL SCIENCE

SIRT1 RNAi knockdown induces apoptosis and senescence, inhibits invasion and enhances chemosensitivity in pancreatic cancer cells

(2011) G Zhao et al.   GENE THERAPY

Response and prognosis of taxanes and anthracyclines neoadjuvant chemotherapy in patients with triple-negative breast cancer

(2011) Jiannan Wu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

ATM and p53 Regulate FOXM1 Expression via E2F in Breast Cancer Epirubicin Treatment and Resistance

(2011) J. Millour et al.   MOLECULAR CANCER THERAPEUTICS

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

(2011) Z. Mao et al.   SCIENCE

Interplay between SIRT proteins and tumour suppressor transcription factors in chemotherapeutic resistance of cancer

(2010) Yolanda Olmos et al.   DRUG RESISTANCE UPDATES

Constitutively Nuclear FOXO3a Localization Predicts Poor Survival and Promotes Akt Phosphorylation in Breast Cancer

(2010) Jie Chen et al.   PLoS One

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity

(2010) B. Schwer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human SIRT6 Promotes DNA End Resection Through CtIP Deacetylation

(2010) Abderrahmane Kaidi et al.   SCIENCE

Chromatin regulation and genome maintenance by mammalian SIRT6

(2010) Ruth I. Tennen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Treatment Options for Breast Cancer Resistant to Anthracycline and Taxane

(2009) Alvaro Moreno-Aspitia et al.   MAYO CLINIC PROCEEDINGS

A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells

(2008) Keitaro Kojima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Phase II Study of Capecitabine and Vinorelbine in Patients with Metastatic Breast Cancer Pretreated with Anthracyclines and Taxanes

(2008) Laura G. Estévez et al.   Clinical Breast Cancer

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE

Emerging Agents in the Treatment of Anthracycline- and Taxane-Refractory Metastatic Breast Cancer

(2008) Windy Dean-Colomb et al.   SEMINARS IN ONCOLOGY

Cellular Mechanisms of Resistance to Anthracyclines and Taxanes in Cancer: Intrinsic and Acquired

(2008) A. Jo Chien et al.   SEMINARS IN ONCOLOGY