Omega-3 polyunsaturated fatty acids selectively inhibit growth in neoplastic oral keratinocytes by differentially activating ERK1/2

p53, ROS and senescence in the control of aging

(2016) Arnaud Vigneron et al.   Aging-US

Adaptive and innovative Radiation Treatment FOR improving Cancer treatment outcomE (ARTFORCE); a randomized controlled phase II trial for individualized treatment of head and neck cancer

(2013) Jolien Heukelom et al.   BMC CANCER

Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases

(2012) Ann R. Finch et al.   CELLULAR SIGNALLING

Mechanisms of Action of (n-3) Fatty Acids

(2012) Philip C. Calder   JOURNAL OF NUTRITION

Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway

(2011) H. Sun et al.   CARCINOGENESIS

Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF- 

(2011) K. H. Weylandt et al.   CARCINOGENESIS

Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis

(2011) Alyssa L. Kennedy et al.   MOLECULAR CELL

Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases

(2010) Gayani Nadika Pitiyage et al.   JOURNAL OF PATHOLOGY

Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer

(2009) Simona Serini et al.   APOPTOSIS

UV-induced squamous cell carcinoma - a role for antiapoptotic signalling pathways

(2009) P.M. Rodust et al.   BRITISH JOURNAL OF DERMATOLOGY

Antineoplastic Effects of N-3 Polyunsaturated Fatty Acids in Combination With Drugs and Radiotherapy: Preventive and Therapeutic Strategies

(2009) G. Calviello et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Docosahexaenoic acid induces apoptosis in lung cancer cells by increasing MKP-1 and down-regulating p-ERK1/2 and p-p38 expression

(2008) Simona Serini et al.   APOPTOSIS

Reduced Colitis-Associated Colon Cancer in Fat-1 (n-3 Fatty Acid Desaturase) Transgenic Mice

(2008) Q. Jia et al.   CANCER RESEARCH

The potential for treatment with dietary long-chain polyunsaturated n-3 fatty acids during chemotherapy

(2008) Patricia D. Biondo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3β phosphorylation

(2008) Yi Lu et al.   MOLECULAR CANCER THERAPEUTICS