Epigenetic deregulation of the anaplastic lymphoma kinase gene modulates mesenchymal characteristics of oral squamous cell carcinomas

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment

(2015) Alberto M. Martelli et al.   Oncotarget

The transcription factor Snail enhanced the degradation of E-cadherin and desmoglein 2 in oral squamous cell carcinoma cells

(2012) Kenichi Kume et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Anaplastic Lymphoma Kinase as a Potential Therapeutic Target in Ovarian Cancer

(2012) H. Ren et al.   CANCER RESEARCH

Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells

(2012) D. J. Mulholland et al.   CANCER RESEARCH

Paracrine Receptor Activation by Microenvironment Triggers Bypass Survival Signals and ALK Inhibitor Resistance in EML4-ALK Lung Cancer Cells

(2012) T. Yamada et al.   CLINICAL CANCER RESEARCH

Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors

(2012) Zuzana Tothova et al.   CURRENT OPINION IN ONCOLOGY

PDGF mediates TGFβ-induced migration during development of the spinous process

(2012) Ying Wang et al.   DEVELOPMENTAL BIOLOGY

Raf-1, a Potential Therapeutic Target, Mediates Early Steps in Endometriosis Lesion Development by Endometrial Epithelial and Stromal Cells

(2012) Elizabeth M. De La Garza et al.   ENDOCRINOLOGY

Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity

(2012) Y. Kim et al.   GENES & DEVELOPMENT

Detection of EML4-ALK fusion genes in non-small cell lung cancer patients with clinical features associated with EGFR mutations

(2012) Zhou Shaozhang et al.   GENES CHROMOSOMES & CANCER

Targeting ALK in neuroblastoma—preclinical and clinical advancements

(2012) Erica L. Carpenter et al.   Nature Reviews Clinical Oncology

EGF-Induced EMT and Invasiveness in Serous Borderline Ovarian Tumor Cells: A Possible Step in the Transition to Low-Grade Serous Carcinoma Cells?

(2012) Jung-Chien Cheng et al.   PLoS One

Progression of Oral Squamous Cell Carcinoma Accompanied with Reduced E-Cadherin Expression but Not Cadherin Switch

(2012) Takashi Hashimoto et al.   PLoS One

ALK signaling and target therapy in anaplastic large cell lymphoma

(2012) Fabrizio Tabbó   Frontiers in Oncology

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts

(2011) Lu Tang et al.   ARCHIVES OF ORAL BIOLOGY

Insights into ALK-Driven Cancers Revealed through Development of Novel ALK Tyrosine Kinase Inhibitors

(2011) C. M. Lovly et al.   CANCER RESEARCH

FGFR3 Is Overexpressed Waldenstrom Macroglobulinemia and Its Inhibition by Dovitinib Induces Apoptosis and Overcomes Stroma-Induced Proliferation

(2011) A. K. Azab et al.   CLINICAL CANCER RESEARCH

Prognostic significance of immunohistochemical biomarkers in oral squamous cell carcinoma

(2011) L.R. Oliveira et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer

(2011) Natalie Ludyga et al.   Molecular BioSystems

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains

(2011) Benjamin P Berman et al.   NATURE GENETICS

High Resolution Detection and Analysis of CpG Dinucleotides Methylation Using MBD-Seq Technology

(2011) Xun Lan et al.   PLoS One

Oral squamous cell cancer: early detection and the role of alcohol and smoking

(2011) Anna G Zygogianni et al.   Head and Neck Optical Diagnostics Society

The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM

(2010) Stephen B. Edge et al.   ANNALS OF SURGICAL ONCOLOGY

Interaction of p53 with Tumor Suppressive and Oncogenic Signaling Pathways to Control Cellular Reactive Oxygen Species Production

(2010) María Fátima Ladelfa et al.   ANTIOXIDANTS & REDOX SIGNALING

Northwestern China: a place to learn more on oesophageal cancer. Part one: behavioural and environmental risk factors

(2010) ShuTao Zheng et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping

(2010) P.-Y. Hsu et al.   GENOME RESEARCH

Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation

(2010) M. D. Robinson et al.   GENOME RESEARCH

Understanding oral cancer in the genome era

(2010) Chi T. Viet et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Frequent Deregulations in the Hedgehog Signaling Network and Cross-Talks with the Epidermal Growth Factor Receptor Pathway Involved in Cancer Progression and Targeted Therapies

(2010) M. Mimeault et al.   PHARMACOLOGICAL REVIEWS

PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma

(2010) Tiziana Bachetti et al.   PLoS One

Oral squamous cell carcinoma and cultural oral risk habits in Vietnam

(2010) SL Priebe et al.   International Journal of Dental Hygiene

Seed in soil, with an epigenetic view

(2008) Huey-Jen L. Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Death Effector Domain-Containing Proteins

(2008) M. Gudur Valmiki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning

(2008) Shawn J. Cokus et al.   NATURE

Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating β2 integrins

(2008) Jingsong Xu et al.   NATURE IMMUNOLOGY

Global epidemiology of oral and oropharyngeal cancer

(2008) Saman Warnakulasuriya   ORAL ONCOLOGY