Cardiac glycosides block cancer growth through HIF-1α- and NF-κB-mediated Plk1

HIF-1α-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism

(2012) Linna Fu et al.   CARCINOGENESIS

Systemic Hypertension

(2011) Christopher Hauck et al.   Cardiology in Review

PLK1 Is Transcriptionally Activated by NF- B during Cell Detachment and Enhances Anoikis Resistance through Inhibiting  -Catenin Degradation in Esophageal Squamous Cell Carcinoma

(2011) D.-C. Lin et al.   CLINICAL CANCER RESEARCH

Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation

(2011) Chuan-Ming Xie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardiotonic steroids attenuate ERK phosphorylation and generate cell cycle arrest to block human hepatoma cell growth

(2011) Zhong-Wei Xu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells

(2011) Hosam A. Elbaz et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells

(2010) Tom Juncker et al.   BIOCHEMICAL PHARMACOLOGY

Persistent p21 Expression after Nutlin-3a Removal Is Associated with Senescence-like Arrest in 4N Cells

(2010) Hong Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenomatous Polyposis Coli and Hypoxia-inducible Factor-1α Have an Antagonistic Connection

(2010) Ian P. Newton et al.   MOLECULAR BIOLOGY OF THE CELL

Aurora B kinase activation requires survivin priming phosphorylation by PLK1

(2010) Youjun Chu et al.   Journal of Molecular Cell Biology

Oleandrin-mediated inhibition of human tumor cell proliferation: Importance of Na,K-ATPase   subunits as drug targets

(2009) P. Yang et al.   MOLECULAR CANCER THERAPEUTICS

LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner

(2008) Kenichiro Nishi et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of hypoxia-inducible factor-1α by NF-κB

(2008) Patrick van Uden et al.   BIOCHEMICAL JOURNAL

Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora

(2008) Eunice H. Y. Chan et al.   CHROMOSOMA

Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1

(2008) Mark Petronczki et al.   DEVELOPMENTAL CELL

Na+/K+-ATPase α subunits as new targets in anticancer therapy

(2008) Tatjana Mijatovic et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Fast degradation of the auxiliary subunit of Na+/K+-ATPase in the plasma membrane of HeLa cells

(2008) S. H. Yoshimura et al.   JOURNAL OF CELL SCIENCE

Digoxin and other cardiac glycosides inhibit HIF-1  synthesis and block tumor growth

(2008) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA