Degradation of NF-κB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells

Cytotoxic studies of anti-neoplastic drugs on human lymphocytes – In vitro studies

(2017) I. Vamshi Krishna et al.   Cancer Biomarkers

Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide

(2015) Joanna Triscott et al.   Oncotarget

Proteasome inhibitors in multiple myeloma: 10 years later

(2012) P. Moreau et al.   BLOOD

Electrophilic Adduction of Ubiquitin Activating Enzyme E1 by N,N-Diethyldithiocarbamate Inhibits Ubiquitin Activation and Is Accompanied by Striatal Injury in the Rat

(2012) Olga M. Viquez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

The Efficacy of Disulfiram for the Treatment of Alcohol Use Disorder

(2011) Charlotte H. Jørgensen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Redox Regulation of p53, Redox Effectors Regulated by p53: A Subtle Balance

(2011) Agnès Maillet et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action

(2011) Jennie L. Williams et al.   EXPERIMENTAL CELL RESEARCH

Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity and disease

(2011) Haider Raza   FEBS Journal

S-Glutathionylation of Cysteine 99 in the APE1 Protein Impairs Abasic Endonuclease Activity

(2011) Yun-Jeong Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

The Drug-Induced Degradation of Oncoproteins: An Unexpected Achilles' Heel of Cancer Cells?

(2011) Julien Ablain et al.   Cancer Discovery

A novel dithiocarbamate analogue with potentially decreased ALDH inhibition has copper-dependent proteasome-inhibitory and apoptosis-inducing activity in human breast cancer cells

(2010) Fei Wang et al.   CANCER LETTERS

Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines

(2010) Mohd. A. Yusuf et al.   FREE RADICAL BIOLOGY AND MEDICINE

Direct Covalent Modification as a Strategy to Inhibit Nuclear Factor-Kappa B

(2009) V. Pande et al.   CURRENT MEDICINAL CHEMISTRY

Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination

(2009) James M. Baugh et al.   JOURNAL OF MOLECULAR BIOLOGY

The redox switch: dynamic regulation of protein function by cysteine modifications

(2009) Davide Spadaro et al.   PHYSIOLOGIA PLANTARUM

Apurinic/Apyrimidinic Endonuclease/Redox Effector Factor-1(APE/Ref-1): A Unique Target for the Prevention and Treatment of Human Melanoma

(2008) Sun Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

(2008) Jan S Moreb et al.   Molecular Cancer