Hypoxia-inducible factor-2  is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer

Progression of Pancreatic Adenocarcinoma Is Significantly Impeded with a Combination of Vaccine and COX-2 Inhibition

(2014) P. Mukherjee et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-Inducible Factor-2  Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis

(2012) X. Xue et al.   CANCER RESEARCH

The Interplay between Indoleamine 2,3-Dioxygenase 1 (IDO1) and Cyclooxygenase (COX)-2 In Chronic Inflammation and Cancer

(2012) A. Cesario et al.   CURRENT MEDICINAL CHEMISTRY

Prostaglandin E2 promotes intestinal tumor growth via DNA methylation

(2012) Dianren Xia et al.   NATURE MEDICINE

COX-2 Inhibitors and Cardiovascular Risk

(2012) C. P. Cannon et al.   SCIENCE

Identification and development of mPGES-1 inhibitors: where we are at?

(2011) Hui-Hua Chang et al.   Future Medicinal Chemistry

Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

(2011) Matthew Taylor et al.   GASTROENTEROLOGY

Molecular Docking and Competitive Binding Study Discovered Different Binding Modes of Microsomal Prostaglandin E Synthase-1 Inhibitors

(2011) Shan He et al.   Journal of Chemical Information and Modeling

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis

(2011) Y Sasaki et al.   ONCOGENE

Hydroxyamidine Inhibitors of Indoleamine-2,3-dioxygenase Potently Suppress Systemic Tryptophan Catabolism and the Growth of IDO-Expressing Tumors

(2010) H. K. Koblish et al.   MOLECULAR CANCER THERAPEUTICS

HIF-1 and HIF-2 transcription factors — Similar but not identical

(2010) Agnieszka Loboda et al.   MOLECULES AND CELLS

Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis

(2009) James J. Lee et al.   CARCINOGENESIS

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

(2009) Yatrik M. Shah et al.   Cell Metabolism

Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression

(2008) Mazin A. Al-Salihi et al.   CANCER LETTERS

Genetic Deletion of mPGES-1 Suppresses Intestinal Tumorigenesis

(2008) M. Nakanishi et al.   CANCER RESEARCH