Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation

Exposure to Nicotine and Carcinogens among Southwestern Alaskan Native Cigarette Smokers and Smokeless Tobacco Users

(2012) N. L. Benowitz et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people

(2012) Matthew J. Binnington et al.   Pharmacogenetics and Genomics

Urinary levels of the tobacco-specific carcinogen N'-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers

(2011) J.-M. Yuan et al.   CARCINOGENESIS

Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)

(2011) Monica Ter-Minassian et al.   INTERNATIONAL JOURNAL OF CANCER

Time Course of Nicotine and Cotinine Incorporation into Samples of Nonsmokers' Beard Hair Following a Single Dose of Nicotine Polacrilex*

(2011) John T. Bernert et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Relationship Between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 Variation and Smoking Behaviors and Lung Cancer Risk

(2011) Catherine A. Wassenaar et al.   JNCI-Journal of the National Cancer Institute

Comparison of Urine Cotinine and the Tobacco-Specific Nitrosamine Metabolite 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol (NNAL) and Their Ratio to Discriminate Active From Passive Smoking

(2011) Maciej Lukasz Goniewicz et al.   NICOTINE & TOBACCO RESEARCH

Racial Differences in the Relationship Between Number of Cigarettes Smoked and Nicotine and Carcinogen Exposure

(2011) N. L. Benowitz et al.   NICOTINE & TOBACCO RESEARCH

Urine Menthol as a Biomarker of Mentholated Cigarette Smoking

(2010) N. L. Benowitz et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Genetic Variation in Nicotine Metabolism Predicts the Efficacy of Extended-Duration Transdermal Nicotine Therapy

(2010) C Lerman et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Utility and Relationships of Biomarkers of Smoking in African-American Light Smokers

(2009) M. K. Ho et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Elimination Kinetics of the Tobacco-Specific Biomarker and Lung Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol

(2009) M. L. Goniewicz et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers

(2009) J.-M. Yuan et al.   CANCER RESEARCH

Association of Nicotine Metabolite Ratio and CYP2A6 Genotype With Smoking Cessation Treatment in African-American Light Smokers

(2009) MK Ho et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors

(2009) Nael Al Koudsi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Subpicogram per Milliliter Determination of the Tobacco-Specific Carcinogen Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Human Urine Using Liquid Chromatography−Tandem Mass Spectrometry

(2008) Peyton Jacob et al.   ANALYTICAL CHEMISTRY

Extensive Metabolic Activation of the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Smokers

(2008) I. Stepanov et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

(2008) L. Le Marchand et al.   CANCER RESEARCH

Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent

(2008) Jill C. Mwenifumbo et al.   HUMAN MUTATION

CYP2A6polymorphisms and risk for tobacco-related cancers

(2008) Ana Rossini et al.   PHARMACOGENOMICS