DNA methylation of microRNA genes in multiple myeloma

Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells

(2012) Hsing-Chen Tsai et al.   CANCER CELL

DNA Methylation Profiling Defines Clinically Relevant Biological Subsets of Non-Small Cell Lung Cancer

(2012) K. Walter et al.   CLINICAL CANCER RESEARCH

Epigenetic inactivation of the MIR34B/C in multiple myeloma

(2011) K. Y. Wong et al.   BLOOD

MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma

(2011) Amanda Tivnan et al.   BMC CANCER

Epigenetic silencing of MIR203 in multiple myeloma

(2011) Kwan-Yeung Wong et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cancer statistics, 2011

(2011) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Deregulated microRNAs in multiple myeloma

(2011) Leonidas Benetatos et al.   CANCER

Mechanisms of microRNA deregulation in human cancer

(2011) Shan Deng et al.   CELL CYCLE

Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

(2011) J. H. Kim et al.   GENOME RESEARCH

Epigenetic inactivation of the hsa-miR-203 in haematological malignancies

(2011) Chor Sang Chim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms

(2011) Chor Sang Chim et al.   Journal of Translational Medicine

MicroRNA signatures characterize multiple myeloma patients

(2011) S L Corthals et al.   LEUKEMIA

Epigenetic Inactivation of the miR-124-1 in Haematological Malignancies

(2011) Kwan Yeung Wong et al.   PLoS One

Wild-type p53 controls cell motility and invasion by dual regulation of MET expression

(2011) C.-I. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation of tumor suppressor miRNA genes: a lesson from themiR-34family

(2011) Kwan Yeung Wong et al.   Epigenomics

MicroRNAs: New Players in Multiple Myeloma

(2011) Flavia Pichiorri et al.   Frontiers in Genetics

MicroRNA-34a: A Novel Tumor Suppressor in p53-mutant Glioma Cell Line U251

(2010) Shihai Luan et al.   ARCHIVES OF MEDICAL RESEARCH

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

(2010) B. A. Walker et al.   BLOOD

Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing

(2010) Yoshinao Ruike et al.   BMC GENOMICS

Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer

(2010) H H Cheung et al.   BRITISH JOURNAL OF CANCER

Plasma cell leukaemia and other aggressive plasma cell malignancies

(2010) Taimur Sher et al.   BRITISH JOURNAL OF HAEMATOLOGY

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

(2010) S. Jiang et al.   CANCER RESEARCH

The Promise of MicroRNA Replacement Therapy

(2010) A. G. Bader et al.   CANCER RESEARCH

Epigenetic inactivation of the miR-34a in hematological malignancies

(2010) C.S. Chim et al.   CARCINOGENESIS

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

Frequent Downregulation of miR-34 Family in Human Ovarian Cancers

(2010) D. C. Corney et al.   CLINICAL CANCER RESEARCH

DNA methylation profiling in cancer

(2010) Yutaka Kondo et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Bortezomib Plus Dexamethasone Induction Improves Outcome of Patients With t(4;14) Myeloma but Not Outcome of Patients With del(17p)

(2010) Hervé Avet-Loiseau et al.   JOURNAL OF CLINICAL ONCOLOGY

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling

(2010) N C Gutiérrez et al.   LEUKEMIA

Identification of a novel microRNA clustermiR-193b-365in multiple myeloma

(2010) Kenji Unno et al.   LEUKEMIA & LYMPHOMA

Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer

(2010) Saskia M Wilting et al.   Molecular Cancer

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

High-risk myeloma is associated with global elevation of miRNAs and overexpression ofEIF2C2/AGO2

(2010) Yiming Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Drugs Take On Cancer

(2010) Jocelyn Kaiser   SCIENCE

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1

(2009) R. Garzon et al.   BLOOD

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial

(2009) T. Zenz et al.   BLOOD

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma

(2009) M. Lionetti et al.   BLOOD

MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

(2009) A. M. Roccaro et al.   BLOOD

miR-34b Targets Cyclic AMP-Responsive Element Binding Protein in Acute Myeloid Leukemia

(2009) M. Pigazzi et al.   CANCER RESEARCH

Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia

(2009) X. Agirre et al.   CANCER RESEARCH

miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer

(2009) Elena Gallardo et al.   CARCINOGENESIS

miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma

(2009) Mayuko Furuta et al.   CARCINOGENESIS

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles

(2009) Marta Lionetti et al.   GENES CHROMOSOMES & CANCER

MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis

(2009) N. Felli et al.   HAEMATOLOGICA

Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: support for genetic factors in pathogenesis

(2009) O Landgren et al.   LEUKEMIA

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review

(2009) R Fonseca et al.   LEUKEMIA

miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities

(2009) M Mraz et al.   LEUKEMIA

MicroRNAs in chronic lymphocytic leukemia pathogenesis and disease subtypes

(2009) Marek Mraz et al.   LEUKEMIA & LYMPHOMA

Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma

(2009) Sophie L. Corthals et al.   LEUKEMIA RESEARCH

MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets

(2009) M. T. N. Le et al.   MOLECULAR AND CELLULAR BIOLOGY

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers

(2009) Mayumi Oda et al.   NUCLEIC ACIDS RESEARCH

Epigenetic alterations in cervical carcinogenesis

(2009) Anita Szalmás et al.   SEMINARS IN CANCER BIOLOGY

Methods in DNA methylation profiling

(2009) Tao Zuo et al.   Epigenomics

Current status of epigenetic treatment in myelodysplastic syndromes

(2008) Andrea Kuendgen et al.   ANNALS OF HEMATOLOGY

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

miR-34a as part of the resistance network in chronic lymphocytic leukemia

(2008) T. Zenz et al.   BLOOD

Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

(2008) Qing Ji et al.   BMC CANCER

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression

(2008) María J. Bueno et al.   CANCER CELL

Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer

(2008) M. Toyota et al.   CANCER RESEARCH

MicroRNAs in normal and malignant hematopoiesis

(2008) Ramiro Garzon et al.   CURRENT OPINION IN HEMATOLOGY

Breast cancer epigenetics: normal human mammary epithelial cells as a model system

(2008) Rebecca A. Hinshelwood et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulation

(2008) M K Dijkstra et al.   LEUKEMIA

Clinical and biological significance of RAS mutations in multiple myeloma

(2008) W J Chng et al.   LEUKEMIA

Bone marrow microenvironment and the identification of new targets for myeloma therapy

(2008) K Podar et al.   LEUKEMIA

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death

(2008) R Schickel et al.   ONCOGENE

p16INK4a Translation Suppressed by miR-24

(2008) Ashish Lal et al.   PLoS One

Aberrant Expression of Oncogenic and Tumor-Suppressive MicroRNAs in Cervical Cancer Is Required for Cancer Cell Growth

(2008) Xiaohong Wang et al.   PLoS One

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

(2008) F. Pichiorri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA