Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells

Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation

(2012) Mizuho Kikuyama et al.   CANCER LETTERS

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk

(2012) Arie B. Brinkman et al.   GENOME RESEARCH

Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

(2011) Stefan Enroth et al.   BMC CANCER

Effects of genome architecture and epigenetic factors on susceptibility of promoter CpG islands to aberrant DNA methylation induction

(2011) Hideyuki Takeshima et al.   GENOMICS

Quantitative analyses of DAPK1 methylation in AML and MDS

(2011) Rainer Claus et al.   INTERNATIONAL JOURNAL OF CANCER

Early-stage formation of an epigenetic field defect in a mouse colitis model and non-essential roles of T- and B-cells in DNA methylation induction

(2011) M Katsurano et al.   ONCOGENE

Inflammatory Processes Triggered by Helicobacter pylori Infection Cause Aberrant DNA Methylation in Gastric Epithelial Cells

(2010) T. Niwa et al.   CANCER RESEARCH

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

(2010) Till Bartke et al.   CELL

Epigenetic inheritance through self-recruitment of the polycomb repressive complex 2

(2010) Klaus Hansen et al.   Epigenetics

Methylation destiny: Moira takes account of histones and RNA polymerase II

(2010) Hideyuki Takeshima et al.   Epigenetics

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate

(2010) F Liu et al.   ONCOGENE

Aberrant DNA methylation in contrast with mutations

(2009) Toshikazu Ushijima et al.   CANCER SCIENCE

Alterations of histone modifications by cobalt compounds

(2009) Qin Li et al.   CARCINOGENESIS

The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands

(2009) H. Takeshima et al.   GENOME RESEARCH

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

(2009) T. B. Miranda et al.   MOLECULAR CANCER THERAPEUTICS

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

Methylation of Polycomb Target Genes in Intestinal Cancer Is Mediated by Inflammation

(2008) M. A. Hahn et al.   CANCER RESEARCH

A Multifactorial Signature of DNA Sequence and Polycomb Binding Predicts Aberrant CpG Island Methylation

(2008) M. T. McCabe et al.   CANCER RESEARCH

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

(2008) Satoshi Fujii et al.   CANCER SCIENCE

Aberrant methylation of the death-associated protein kinase 1 (DAPK1) CpG island in chronic myeloid leukemia

(2008) Jun Qian et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The presence of a methylation fingerprint ofHelicobacter pyloriinfection in human gastric mucosae

(2008) Takeshi Nakajima et al.   INTERNATIONAL JOURNAL OF CANCER

Enhancer of Zeste Homologue 2 (EZH2) Down-regulates RUNX3 by Increasing Histone H3 Methylation

(2008) Satoshi Fujii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

(2008) Yutaka Kondo et al.   NATURE GENETICS

Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

(2008) E. N. Gal-Yam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA