Smad phosphoisoform signaling specificity: the right place at the right time

Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro

(2011) M P Serres et al.   ONCOGENE

c-Jun N-Terminal Kinase 1 Promotes Transforming Growth Factor–β1–Induced Epithelial-to-Mesenchymal Transition via Control of Linker Phosphorylation and Transcriptional Activity of Smad3

(2010) Jos L. J. van der Velden et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

SKI promotes Smad3 linker phosphorylations associated with the tumor-promoting trait of TGF-β

(2010) Qiushi Lin et al.   CELL CYCLE

TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2

(2010) Micah L. Burch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis

(2010) Seiji Kawamata et al.   INFLAMMATORY BOWEL DISEASES

Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells

(2010) M. Sasseville et al.   JOURNAL OF CELL SCIENCE

14-3-3 sigma and 14-3-3 zeta plays an opposite role in cell growth inhibition mediated by transforming growth factor-beta 1

(2010) Hye-Young Hong et al.   MOLECULES AND CELLS

Increased cell migration and plasticity in Nrf2-deficient cancer cell lines

(2010) G Rachakonda et al.   ONCOGENE

Novel Regulation of Smad3 Oligomerization and DNA Binding by Its Linker Domain

(2009) Eleftheria Vasilaki et al.   BIOCHEMISTRY

Mechanisms of transforming growth factor β1/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts

(2009) S. He et al.   BRITISH JOURNAL OF DERMATOLOGY

Smad2 and Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions Transmit Malignant TGF-β Signal in Later Stages of Human Colorectal Cancer

(2009) Koichi Matsuzaki et al.   CANCER RESEARCH

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The ups and downs of Myc biology

(2009) Laura Soucek et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma

(2009) Hiromitsu Nagata et al.   HEPATOLOGY

Transforming Growth Factor-β-inducible Phosphorylation of Smad3

(2009) Guannan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Negative Feedback Control of Transforming Growth Factor-β Signaling by Glycogen Synthase Kinase 3-mediated Smad3 Linker Phosphorylation at Ser-204

(2009) Caroline Millet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pin1 Down-regulates Transforming Growth Factor-β (TGF-β) Signaling by Inducing Degradation of Smad Proteins

(2009) Ayako Nakano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pin1 Promotes Transforming Growth Factor-β-induced Migration and Invasion

(2009) Isao Matsuura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitin Ligase Nedd4L Targets Activated Smad2/3 to Limit TGF-β Signaling

(2009) Sheng Gao et al.   MOLECULAR CELL

Phospho-control of TGF-β superfamily signaling

(2008) Katharine H Wrighton et al.   CELL RESEARCH

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Role of Ras Signaling in the Induction of Snail by Transforming Growth Factor-β

(2008) Kana Horiguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compound Astragalus and Salvia miltiorrhiza Extract exerts anti-fibrosis by mediating TGF-β/Smad signaling in myofibroblasts

(2008) Yan Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE