Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells

Direct Inhibition of Elastase Activity by Indole-3-Carbinol Triggers a CD40-TRAF Regulatory Cascade That Disrupts NF-κB Transcriptional Activity in Human Breast Cancer Cells

(2010) Ida Aronchik et al.   CANCER RESEARCH

1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells

(2010) Hanh H. Nguyen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anticancer Properties of Indole Compounds: Mechanism of Apoptosis Induction and Role in Chemotherapy

(2010) Aamir Ahmad et al.   CURRENT DRUG TARGETS

Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop

(2010) Crystal N. Marconett et al.   MOLECULAR BIOLOGY OF THE CELL

Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol

(2009) T. Melkamu et al.   CARCINOGENESIS

Telomerase: cellular immortalization and neoplastic transformation. Multiple functions of a multifaceted complex

(2009) C. Belgiovine et al.   CYTOGENETIC AND GENOME RESEARCH

Minireview: Modulation of Hormone Receptor Signaling by Dietary Anticancer Indoles

(2009) Gary L. Firestone et al.   MOLECULAR ENDOCRINOLOGY

Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol

(2009) Yoshiaki Machijima et al.   Retrovirology

Cancer chemotherapy with indole-3-carbinol, bis(3′-indolyl)methane and synthetic analogs

(2008) Stephen Safe et al.   CANCER LETTERS

Understanding and exploitinghTERTpromoter regulation for diagnosis and treatment of human cancers

(2008) Satoru Kyo et al.   CANCER SCIENCE

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

(2008) S. N. Sundar et al.   CARCINOGENESIS

Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity

(2008) Christine T. Brew et al.   INTERNATIONAL JOURNAL OF CANCER

The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing

(2008) H. H. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice

(2007) Einat Souli et al.   FOOD AND CHEMICAL TOXICOLOGY

3,3′-Diindolylmethane stimulates murine immune function in vitro and in vivo

(2007) L XUE et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY