PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer

Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis

(2011) Shouye Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Distinct Biological Roles for the Akt Family in Mammary Tumor Progression: Figure 1.

(2010) Rachelle L. Dillon et al.   CANCER RESEARCH

Akt isoforms regulate intermediate filament protein levels in epithelial carcinoma cells

(2010) Anne-Marie Fortier et al.   FEBS LETTERS

Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer

(2010) Todd W. Miller et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging Targeted Therapies for Breast Cancer

(2010) Ricardo H. Alvarez et al.   JOURNAL OF CLINICAL ONCOLOGY

Responsiveness to PI3K and MEK Inhibitors in Breast Cancer. Use of a 3D Culture System to Study Pathways Related to Hormone Independence in Mice

(2010) Maria Laura Polo et al.   PLoS One

Inhibition of mammary tumor growth by estrogens: is there a specific role for estrogen receptors alpha and beta?

(2009) Rocío Soldati et al.   BREAST CANCER RESEARCH AND TREATMENT

Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer

(2009) T. W. Miller et al.   CANCER RESEARCH

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer

(2009) Claudia Lanari et al.   ENDOCRINE-RELATED CANCER

Novel human breast cancer cell lines IBH-4, IBH-6, and IBH-7 growing in nude mice

(2009) Ariana Bruzzone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of Mammary Stem/Progenitor Cells by PTEN/Akt/β-Catenin Signaling

(2009) Hasan Korkaya et al.   PLOS BIOLOGY

Tamoxifen Resistance in Breast Tumors Is Driven by Growth Factor Receptor Signaling with Repression of Classic Estrogen Receptor Genomic Function

(2008) S. Massarweh et al.   CANCER RESEARCH

Targeted therapies in breast cancer: Where are we now?

(2008) Serena Di Cosimo et al.   EUROPEAN JOURNAL OF CANCER

Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis

(2008) Sebastián Giulianelli et al.   INTERNATIONAL JOURNAL OF CANCER

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution

(2008) Ioanna G. Maroulakou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The PTEN–PI3K pathway: of feedbacks and cross-talks

(2008) A Carracedo et al.   ONCOGENE