Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett’s oesophageal adenocarcinoma

The Clonal Origins of Dysplasia From Intestinal Metaplasia in the Human Stomach

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The role of secondary bile acids in neoplastic development in the oesophagus

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Immunity, Inflammation, and Cancer

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Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis

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Up-regulation of Activation-Induced Cytidine Deaminase Causes Genetic Aberrations at the CDKN2b-CDKN2a in Gastric Cancer

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MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo

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Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells

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Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

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Barrett's oesophagus

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Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells

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Bile Acid Exposure Up-regulates Tuberous Sclerosis Complex 1/Mammalian Target of Rapamycin Pathway in Barrett's-Associated Esophageal Adenocarcinoma

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Activation-Induced Cytidine Deaminase Links Between Inflammation and the Development of Colitis-Associated Colorectal Cancers

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Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus

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Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma

(2008) Junji Komori et al.   HEPATOLOGY

Aberrant AID expression and human cancer development

(2008) Hiroyuki Marusawa   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

(2008) Toshiyuki Morisawa et al.   INTERNATIONAL JOURNAL OF CANCER

The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF- B activation in oesophageal cells, with a mechanism of action involving ROS

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Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

p16 Mutation Spectrum in the Premalignant Condition Barrett's Esophagus

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