Senescence: an antiviral defense that is tumor suppressive?

Relation between replicative senescence of human fibroblasts and life history characteristics

(2009) Andrea B. Maier et al.   AGEING RESEARCH REVIEWS

Syndromes of Telomere Shortening

(2009) Mary Armanios   Annual Review of Genomics and Human Genetics

Control of telomere length by a trimming mechanism that involves generation of t-circles

(2009) Hilda A Pickett et al.   EMBO JOURNAL

Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging

(2009) George W. Hinkal et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression

(2009) Andrea Proctor Subhawong et al.   MODERN PATHOLOGY

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence

(2009) Kaori Fujita et al.   NATURE CELL BIOLOGY

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT

(2009) K Lafferty-Whyte et al.   ONCOGENE

A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis

(2009) A. S. Venteicher et al.   SCIENCE

Amplification of Telomerase Reverse Transcriptase Gene in Human Mammary Epithelial Cells with Limiting Telomerase RNA Expression Levels

(2008) Y. Cao et al.   CANCER RESEARCH

Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

(2008) Ying Cao et al.   CANCER SCIENCE

Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly

(2008) Andrew S. Venteicher et al.   CELL

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Multiple Mechanisms of Telomere Maintenance Exist and Differentially Affect Clinical Outcome in Diffuse Malignant Peritoneal Mesothelioma

(2008) R. Villa et al.   CLINICAL CANCER RESEARCH

Cellular senescence in vivo: a barrier to tumorigenesis

(2008) Alexandre Prieur et al.   CURRENT OPINION IN CELL BIOLOGY

Telomere elongation involves intra-molecular DNA replication in cells utilizing alternative lengthening of telomeres

(2008) A. Muntoni et al.   HUMAN MOLECULAR GENETICS

Interferon-γ induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells

(2008) Kwang Seok Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Human UBN1 Is an Ortholog of Yeast Hpc2p and Has an Essential Role in the HIRA/ASF1a Chromatin-Remodeling Pathway in Senescent Cells

(2008) G. Banumathy et al.   MOLECULAR AND CELLULAR BIOLOGY

Critical pathways in cellular senescence and immortalization revealed by gene expression profiling

(2008) A L Fridman et al.   ONCOGENE