New synthetic AICAR derivatives with enhanced AMPK and ACC activation

Small Molecule Adenosine 5′-Monophosphate Activated Protein Kinase (AMPK) Modulators and Human Diseases

(2014) Sandeep Rana et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Insight into Adiponectin Role in Obesity and Obesity-Related Diseases

(2014) Ersilia Nigro et al.   Biomed Research International

Chimeric Beta-Defensin Analogs, Including the Novel 3NI Analog, Display Salt-Resistant Antimicrobial Activity and Lack Toxicity in Human Epithelial Cell Lines

(2013) Olga Scudiero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Adiponectin affects lung epithelial A549 cell viability counteracting TNFa and IL-1ß toxicity through AdipoR1

(2013) Ersilia Nigro et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Synthesis of New Acadesine (AICA-riboside) Analogues Having Acyclic d-Ribityl or 4-Hydroxybutyl Chains in Place of the Ribose

(2013) Stefano D'Errico et al.   MOLECULES

AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

(2012) Carlotta Petti et al.   MELANOMA RESEARCH

Abstract A209: The nucleoside analogue acadesine exerts antitumoral activity and cooperates with anti-CD20 monoclonal antibodies in in vitro and in vivo models of mantle cell lymphoma.

(2012) A. Montraveta et al.   MOLECULAR CANCER THERAPEUTICS

Solid-Phase Synthesis of a New Diphosphate 5-Aminoimidazole-4-carboxamide Riboside (AICAR) Derivative and Studies toward Cyclic AICAR Diphosphate Ribose

(2011) Stefano D’Errico et al.   MOLECULES

AICA-riboside (acadesine), an activator of AMP-activated protein kinase with potential for application in hematologic malignancies

(2010) Eric Van Den Neste et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Phospholipase D1 Mediates AMP-Activated Protein Kinase Signaling for Glucose Uptake

(2010) Jong Hyun Kim et al.   PLoS One

A solid-phase approach to the synthesis of N-1-alkyl analogues of cyclic inosine-diphosphate-ribose (cIDPR)

(2010) Giorgia Oliviero et al.   TETRAHEDRON

AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease

(2009) Aaron K. F. Wong et al.   CLINICAL SCIENCE

2′-O-Alkyl Derivatives and 5′-Analogues of 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) as Potential Hsp90 Inhibitors

(2009) Antonio Bracci et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast

(2008) Ji-Eun Kim et al.   BONE

Synthesis of 4-N-alkyl and ribose-modified AICAR analogues on solid support

(2008) Giorgia Oliviero et al.   TETRAHEDRON