Review
Medicine, General & Internal
Jie Li, Xin Huang, Guo Zhong
Summary: This study systematically assesses the efficacy and safety of using vertebroplasty to treat OVCF, and the results will help determine the effectiveness and safety of this therapy for patients.
Article
Clinical Neurology
Ping-Yeh Chiu, Fu-Cheng Kao, Ming-Kai Hsieh, Tsung-Ting Tsai, Wen-Jer Chen, Chi-Chien Niu, Po-Liang Lai
Summary: Among patients with osteoporotic vertebral compression fractures (OVCFs) who underwent vertebral cement augmentation, the incidence of further fractures in sandwich vertebrae is not higher compared to adjacent vertebrae. Male gender was identified as a potential risk factor for sandwich vertebral fractures. Patients with sandwich vertebral fractures may be more likely to pursue surgical intervention than those with only adjacent fractures.
Article
Engineering, Biomedical
Fei Feng, Mengmeng Chen, Xuan Wang, Hongwei Zhang, Hongtao Nie, Hai Tang
Summary: This study investigated the product translation of a spinal acrylic bone cement (ABC) in China. The newly marketed product demonstrated similar properties to the existing product and passed verification tests. It showed good performance in non-clinical and animal experiments, and proved to be safe and effective in a clinical investigation.
BIOACTIVE MATERIALS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Alba Fiorentino, Fabiana Gregucci, Ilaria Bonaparte, Nicola Vitulano, Alessia Surgo, Rosario Mazzola, Antonio Di Monaco, Roberta Carbonara, Filippo Alongi, Tommaso Langialonga, Massimo Grimaldi
Summary: SABR has been used for the treatment of cardiac arrhythmias based on preclinical and clinical data, demonstrating it as a safe and effective noninvasive treatment approach with a good response time of 2-3 months. The treatment dose is crucial for efficacy, and clinical data support the feasibility, effectiveness, and safety of SABR for refractory ventricular arrhythmias.
Article
Anesthesiology
Caroline Tomas, Alexandria Jensen, Farres Ahmed, Corey K. Ho, M. K. Jesse
Summary: This study found that 29.8% of patients had vertebral fracture clefts, while cement nonunion was observed in only 6.8% of cases. Pain improvement outcomes showed that there was no significant difference between patients with clefted and non-clefted compression fractures following cement augmentation.
Article
Oncology
Roman O. Kowalchuk, Benjamin A. Johnson-Tesch, Joseph T. Marion, Trey C. Mullikin, William S. Harmsen, Peter S. Rose, Brittany L. Siontis, Dong Kun Kim, Brian A. Costello, Jonathan M. Morris, Robert W. Gao, Satomi Shiraishi, John J. Lucido, Terence T. Sio, Daniel M. Trifiletti, Kenneth R. Olivier, Dawn Owen, Bradley J. Stish, Mark R. Waddle, Nadia N. Laack, Sean S. Park, Paul D. Brown, Kenneth W. Merrell
Summary: This study aimed to develop and evaluate a risk stratification model for vertebral compression fracture (VCF) after Stereotactic Body Radiation Therapy (SBRT). By studying a cohort of 331 patients, several variables associated with high risk of VCF were identified, and a multivariable Cox model was proposed to predict the risk of VCF accurately.
Article
Endocrinology & Metabolism
W. Ni, C. Ricker, M. Quinn, N. Gasquet, D. Janardhanan, C. J. Gilligan, J. A. Hirsch
Summary: This retrospective analysis of insurance claims examined trends in prescription fills among patients with vertebral compression fractures who underwent balloon kyphoplasty or vertebroplasty. Nearly half of patients with evidence of opioid use reduced or discontinued their prescription fills after surgery, leading to decreased payer costs.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Oncology
Luca Nicosia, Elena Rossato, Renato Avesani, Fabio Marchioretto, Giuseppe Armani, Massimo Zamperini, Giovanni Foti, Fatemeh Jafari, Antonio De Simone, Ruggero Ruggieri, Filippo Alongi, Federico Ferrari
Summary: Spasticity is a clinical condition caused by central nervous system damage, affecting patients' mobility and quality of life. Stereotactic radiosurgery (SRS) may serve as a non-invasive treatment option. This paper presents the preliminary results of the first clinical use of this novel technique.
RADIOTHERAPY AND ONCOLOGY
(2022)
Review
Clinical Neurology
Wei Cheng Chen, Sung Huang Laurent Tsai, Anshit Goyal, Tsai-Sheng Fu, Tung-Yi Lin, Mohamad Bydon
Summary: The study found that vertebroplasty with high viscosity cement had a lower risk of cement leakage compared to low viscosity cement and kyphoplasty, with future prospective studies needed for further validation.
EUROPEAN SPINE JOURNAL
(2021)
Review
Clinical Neurology
Mohammad Daher, Gaby Kreichati, Khalil Kharrat, Amer Sebaaly
Summary: Osteoporotic vertebral compression fractures are a common consequence of osteoporosis and a major healthcare crisis worldwide. The management of these fractures requires pain management and fracture stabilization. A meta-analysis compared vertebroplasty and kyphoplasty in terms of clinical outcomes for these fractures.
WORLD NEUROSURGERY
(2023)
Review
Clinical Neurology
Qiang Wang, Changtai Sun, Liang Zhang, Lin Wang, Quan Ji, Nan Min, Zilong Yin
Summary: This study compared high- versus low-viscosity bone cement in patients with osteoporotic vertebral compression fractures who underwent percutaneous vertebroplasty or percutaneous kyphoplasty. The results showed that high-viscosity cement had a lower leakage rate and was more effective in reducing pain compared to low-viscosity cement.
EUROPEAN SPINE JOURNAL
(2022)
Article
Orthopedics
Zhi Chen, Chenyang Song, Min Chen, Hongxiang Li, Yusong Ye, Wenge Liu
Summary: This study identified risk factors for subsequent fractures in the thoracolumbar segment after vertebral augmentation, including previous fracture, intravertebral cleft, fatty infiltration of psoas, and body angle restoration rate. Refractures were more likely to occur when the body angle restoration rate exceeded 0.350.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Review
Clinical Neurology
Ryan Mattie, Nick Brar, Jennifer T. Tram, Zachary L. McCormick, Douglas P. Beall, Andrew Fox, Mikhail Saltychev
Summary: This study compared vertebral augmentation surgeries with other therapies for cancer-related vertebral compression fractures through meta-analysis of randomized controlled trials, demonstrating a statistically significant pain relief effect. Vertebral augmentation surgeries, such as vertebroplasty and kyphoplasty, showed better outcomes compared to nonsurgical management, radiofrequency ablation, or chemotherapy alone.
Article
Critical Care Medicine
Rupert Schupfner, Katarina Koniarikova, Christian Pfeifer, Peter Grechenig, Bore Bakota, Mario Staresinic, Michael Alexander Kerner, Michael Mueller
Summary: This study compared the transpedicular and extrapedicular approaches to the thoracic spine, showing that the risk of intraspinal malpositioning seems to be lower with the extrapedicular approach in the middle and upper thoracic spine.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Review
Medicine, General & Internal
Stefano Colonna, Andrea Bianconi, Fabio Cofano, Alessandro Prior, Giuseppe Di Perna, Giuseppe Palmieri, Gianluigi Zona, Diego Garbossa, Pietro Fiaschi
Summary: Vertebral body metastases (VBM) are a common site of bone metastasis, and the treatment management presents challenges. Radiofrequency ablation (RFA) is a potential alternative, but it may affect the biomechanics and microanatomy of the vertebral body, increasing the risk of fractures and instability. This study aims to investigate the impact of RFA on spine stability.
Review
Oncology
Albrecht Stenzinger, Arndt Vogel, Ulrich Lehmann, Angela Lamarca, Paul Hofman, Luigi Terracciano, Nicola Normanno
Summary: Cholangiocarcinomas are a heterogeneous group of tumors with distinct genomic alterations. Next-generation sequencing is a powerful tool for identifying gene variants and guiding personalized treatment for patients with cholangiocarcinomas. Understanding the use of NGS in molecular profiling is crucial for healthcare professionals to optimize treatment outcomes.
CANCER TREATMENT REVIEWS
(2024)
