4.6 Review

The contribution of the Epstein-Barr virus to the pathogenesis of childhood lymphomas

Journal

CANCER TREATMENT REVIEWS
Volume 36, Issue 4, Pages 348-353

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.ctrv.2010.02.011

Keywords

EBV; Lymphoma; Childhood; Herpes virus; Therapy

Categories

Funding

  1. Leukaemia Research Fund
  2. Cancer Research UK

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The Epstein-Barr virus (EBV) is a lymphotropic herpes virus with oncogenetic properties which can lead to the development of lymphomas such as Burkitt's lymphoma (BL), Hodgkin's lymphoma (HL), or post-transplant lymphoma. This review discusses our current understanding of lymphomagenesis in relation to EBV and the potential for targeted therapies. (C) 2010 Elsevier Ltd. All rights reserved.

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