S-MDM4 mRNA overexpression indicates a poor prognosis and marks a potential therapeutic target in chronic lymphocytic leukemia

Using the Biology of Chronic Lymphocytic Leukemia to Choose Treatment

(2011) P. Hillmen   Hematology-American Society of Hematology Education Program

The prognostic significance of TP53 mutations in Chinese patients with chronic lymphocytic leukemia is independent of del(17p13)

(2010) Hua-Jie Dong et al.   ANNALS OF HEMATOLOGY

Mechanism of p53 stabilization by ATM after DNA damage

(2010) Qian Cheng et al.   CELL CYCLE

HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis

(2010) Mei Liang et al.   MODERN PATHOLOGY

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial

(2009) T. Zenz et al.   BLOOD

MDM4 (MDMX) and its Transcript Variants

(2009) F. Mancini et al.   CURRENT GENOMICS

The Regulation of the p53-mediated Stress Response by MDM2 and MDM4

(2009) M. E. Perry   Cold Spring Harbor Perspectives in Biology

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

(2008) M. Hallek et al.   BLOOD

Targeting the MDM2-p53 Interaction for Cancer Therapy

(2008) S. Shangary et al.   CLINICAL CANCER RESEARCH

Distinctive IgVH gene segments usage and mutation status in Chinese patients with chronic lymphocytic leukemia

(2008) Lijuan Chen et al.   LEUKEMIA RESEARCH

CD38 as a prognostic factor in Chinese patients with chronic lymphocytic leukaemia

(2008) Wei Xu et al.   LEUKEMIA RESEARCH

Prognostic significance of ATM and TP53 deletions in Chinese patients with chronic lymphocytic leukemia

(2007) Wei Xu et al.   LEUKEMIA RESEARCH