Article
Cardiac & Cardiovascular Systems
Jacqueline K. Olive, Nicolas Zhou, Kyle G. Mitchell, Erin M. Corsini, Wayne L. Hofstetter, Reza J. Mehran, David C. Rice, Boris Sepesi, Stephen G. Swisher, Ara A. Vaporciyan, Garrett L. Walsh, Mara B. Antonoff
Summary: The presence of psychiatric comorbidities in non-small cell lung cancer patients leads to increased 30-day readmissions, but does not affect surgical outcomes or survival rates. Further research is needed to identify the reasons for the increased risk of readmission in patients with psychiatric comorbidities in order to avoid denying surgical care based on these conditions.
ANNALS OF THORACIC SURGERY
(2022)
Article
Oncology
Ting Zhai, Yi Li, Robert Brown, Michael Lanuti, Justin F. Gainor, David C. Christiani
Summary: Pulmonary function can predict overall survival in non-small cell lung cancer (NSCLC) patients. This study evaluates the role of spirometry in predicting NSCLC patients' survival and finds that good pulmonary function at diagnosis may improve patients' overall survival.
Article
Medicine, General & Internal
Samilia Obeng-Gyasi, Yaming Li, William E. Carson, Sarah Reisenger, Carolyn J. Presley, Peter G. Shields, David P. Carbone, DuyKhanh P. Ceppa, Ruth C. Carlos, Barbara L. Andersen
Summary: The study indicates that high allostatic load is associated with adverse social determinants of health and worse overall mortality among patients with advanced lung cancer.
Article
Oncology
Krishna H. Patel, Naomi Alpert, Stephanie Tuminello, Emanuela Taioli
Summary: This study conducted a cohort study to explore how personal and clinical characteristics moderate the effectiveness of chemoimmunotherapy in metastatic non-small cell lung cancer. The results suggest that males may benefit more from chemoimmunotherapy and age, histology, race, and comorbidities may also contribute to differences in effectiveness.
TRANSLATIONAL LUNG CANCER RESEARCH
(2023)
Article
Medicine, General & Internal
Kexun Zhou, Huashan Shi, Ruqin Chen, Jordan J. Cochuyt, David O. Hodge, Rami Manochakian, Yujie Zhao, Sikander Ailawadhi, Yanyan Lou
Summary: Disparities in race and socioeconomic status are associated with outcomes of limited-stage small cell lung cancer (L-SCLC). Racial minorities, including African American and Asian patients, have better survival than White patients for L-SCLC after adjustment for sociodemographic factors. Other factors associated with better survival include female sex, high income, high education, private insurance, diagnostic confirmation by positive cytological analysis, increase in number of regional lymph nodes sampled, and earlier stage at diagnosis.
Article
Oncology
Vera Ehrenstein, Katrine Eriksen, Aliki Taylor, Leslie Servidio, Erik Jakobsen
Summary: This study described the EGFR testing, patient characteristics, and overall survival (OS) among patients with early-stage NSCLC in Denmark. It found that EGFRm-positive status was associated with lower all-cause mortality.
Article
Oncology
Andras Piffko, Benedikt Asey, Lasse Duehrsen, Inka Ristow, Johannes Salamon, Harriet Wikman, Cecile L. Maire, Katrin Lamszus, Manfred Westphal, Thomas Sauvigny, Malte Mohme
Summary: Non-small cell lung cancer is the leading cause of cancer-related death globally, with an increasing incidence of brain metastases in NSCLC patients. This study identified systemic metastatic load and number of brain metastases as significant factors affecting overall survival in resectable NSCLC patients. Factors such as age, absence of other systemic metastases, and number of brain metastases were found to impact survival outcomes.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Raja Flores, Parth Patel, Naomi Alpert, Bruce Pyenson, Emanuela Taioli
Summary: This study found an association between decreased mortality and a corresponding diagnostic shift from later to earlier stage in NSCLC patients. Therefore, studies investigating the effect of treatment on lung cancer must take into account stage shift and the confounding association with survival and mortality outcomes.
Article
Oncology
Jonatan Lindqvist, Antti Jekunen, Eero Sihvo, Mikael Johansson, Heidi Andersen
Summary: This study aimed to evaluate the impact of adherence to first-line treatment guidelines on overall survival in elderly patients with non-small-cell lung cancer (NSCLC) and the reasons for non-adherence. The results showed that guideline adherence was associated with increased overall survival in elderly NSCLC patients, but factors such as age, performance status, and lung function influenced adherence.
Article
Oncology
Viet-Huan Le, Quang-Hien Kha, Truong Nguyen Khanh Hung, Nguyen Quoc Khanh Le
Summary: Despite advancements in lung cancer treatment, the 5-year survival rate remains low. This study aimed to develop a risk score based on CT radiomics to predict survival in NSCLC patients. The risk score model outperformed clinical indicators, and could effectively stratify patients into high and low-risk groups for survival prediction.
Article
Medicine, General & Internal
Shanshan Peng, Yu Xiao, Xinjun Li, Zhanling Wu
Summary: This study aimed to develop a predictive nomogram for the 1- and 2-year overall survival rates in patients with brain metastatic non-small cell lung cancer (BMNSCLC). By collecting patient data and utilizing statistical methods to identify prognostic factors, a nomogram with good predictive ability was developed. The results showed that the nomogram outperformed the TNM staging system in terms of clinical practicability.
Article
Oncology
Khader Shameer, Youyi Zhang, Dan Jackson, Kirsty Rhodes, Imran Khan A. Neelufer, Sreenath Nampally, Andrzej Prokop, Emmette Hutchison, Jiabu Ye, Vladislav A. Malkov, Feng Liu, Antony Sabin, Jim Weatherall, Cristina Duran, Renee Bailey Iacona, Faisal M. Khan, Pralay Mukhopadhyay
Summary: This study compiled data from 81 phase II-IV RCTs of patients with non-small-cell lung cancer and found low-to-moderate correlations between treatment effects for early endpoints (based on PFS) and HR OS across trials of agents with different mechanisms of action. Moderate correlations were seen between treatment effects for HR PFS and HR OS in certain trial subsets.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Kuei-Yuan Hou, Jyun-Ru Chen, Yung-Chen Wang, Ming-Huang Chiu, Sen-Ping Lin, Yuan-Heng Mo, Shih-Chieh Peng, Chia-Feng Lu
Summary: This study aimed to construct a deep learning model combining both radiomic and clinical features to predict the overall survival of patients with NSCLC. The model showed good performance in discriminating high and low risk of survival, and the personalized survival curves generated could be applied for individual OS prediction in clinical practice. Combining pretreatment CECT images, lesion characteristics, and treatment strategies effectively predicted the survival of patients with NSCLC using a deep learning model.
Article
Medicine, General & Internal
Jingsheng Cai, Fan Yang, Xun Wang
Summary: This study aims to investigate occult non-small cell lung cancer (NSCLC), an underappreciated tumor, and found that it is an aggressive tumor with poor prognosis. Surgery is the preferred treatment. More attention should be paid to this overlooked disease due to no evidence of tumor imaging.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medical Laboratory Technology
Jie Yan, Daihong Wan
Summary: This study revealed that elevated circulating CDC42 expression in NSCLC patients is associated with lymph node metastasis, poor DFS, and OS. Additionally, higher TNM stage was also independently correlated with shorter DFS and unsatisfying OS.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2022)
Letter
Dermatology
Rachel Fayne, Mahtab Forouzandeh, Valeria De Bedout, Joshua D. Fox, Mina Zarei, Alyx Rosen, Lilia Fernandez, Claudia Genaro, Feng Miao, Tulay Koru-Sengul, Alberto Caban-Martinez, Robert S. Kirsner, Natasha Schaefer Solle, Natalia Jaimes
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Article
Psychology, Clinical
Taghrid Asfar, Tulay Koru-Sengul, Michael A. Antoni, Asha Dorsey, Estefania C. Ruano Herreria, David J. Lee, Monica Webb Hooper
Summary: This study described lessons learned from recruiting a diverse sample of African American, White, and Hispanic/Latinx smokers in a smoking cessation trial. Word-of-mouth, flyers, newspaper, and online ads were more successful among racial/ethnic minorities. Flyers and newspaper ads were found to be the most economic methods for recruitment.
ADDICTIVE BEHAVIORS
(2022)
Letter
Dermatology
Michael S. Chang, Kevin J. Moore, Rebecca I. Hartman, Tulay Koru-Sengul
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Article
Multidisciplinary Sciences
Heidy N. Medina, Karen E. Callahan, Tulay Koru-Sengul, Sfurti Maheshwari, Qinran Liu, Neha Goel, Paulo S. Pinheiro
Summary: Postmenopausal breast cancer mortality rates are higher among highly-educated Asian women compared to those with lower education levels. This study suggests that the higher educational attainment among Asian women may be associated with an increased incidence of postmenopausal breast cancer.
Article
Oncology
Akina Natori, Vandana Devika Sookdeo, Tulay Koru-Sengul, Matthew Schlumbrecht, Carmen L. Calfa, Jessica Maclntyre, Roberto M. Benzo, Patricia I. Moreno, Tracy E. Crane, Sofia F. Garcia, Frank J. Penedo
Summary: This study found that completing patient-reported outcomes (PRO) assessments based on electronic health records is associated with significantly better clinical outcomes in a diverse cancer population. However, certain patient groups, such as older patients, males, Hispanic/Latino ethnicity, patients without partners, and patients not receiving treatment, were less likely to participate in these assessments. Patients who completed the entire assessment had a lower risk of emergency room visits and hospitalizations.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Addison C. C. Testoff, Natasha Solle, Shirin Shafazand, Paola Louzado-Feliciano, David J. J. Lee, Tulay Koru-Sengul, Erin N. N. Kobetz, Alberto J. J. Caban-Martinez
Summary: Retired firefighters who screen positive for PTSD risk are three times more likely to report delayed sleep onset latency.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Kemi Ogunsina, Tulay Koru-Sengul, Valentina Rodriguez, Alberto J. Caban-Martinez, Natasha Schaefer-Solle, Soyeon Ahn, Erin N. Kobetz, Monique N. Hernandez, David J. Lee
Summary: Firefighters diagnosed with thyroid cancer have a higher odds of having the papillary type compared to other occupational groups, but there is no evidence of an increased odds of rare histologic types or late-stage diagnosis in firefighters compared to other workers.
BMC ENDOCRINE DISORDERS
(2022)
Article
Oncology
Paulo S. Pinheiro, Karen E. Callahan, Heidy N. Medina, Tulay Koru-Sengul, Erin N. Kobetz, Scarlett Lin Gomez, Gilberto de Lima Lopes
Summary: This study provides insights into the incidence rates and trends of lung cancer among never smokers in the United States. LCNS is ranked as the 11th most frequent cancer in men and 8th in women. The study also highlights small differences in LCNS rates among different racial and ethnic groups.
Article
Environmental Sciences
Natasha Schaefer Solle, Amy Legros, Rachael Jackson, Apoorva Rangan, Cynthia Campos Beaver, Hannah Kling, Fatima Khan, Tulay Koru-Sengul, Frank J. Penedo, Alberto J. Caban-Martinez, Erin N. Kobetz
Summary: This study examines cancer survivorship among firefighters and finds that they are exposed to unique carcinogens, but there is limited research on this topic. The results show that firefighters who are cancer survivors have lower levels of emotional well-being but higher quality of life in physical, social, and functional well-being.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Correction
Immunology
Gongzhen Liu, Feng Miao, Yongbin Wang, Jingxuan Kou, Kun Yang, Wei Li, Chunrong Xiong, Fengjian Zhang, Xinyao Wang, Haoyun Yan, Changyin Wei, Changlei Zhao, Ge Yan
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Oncology
Rachelle Brick, Akina Natori, Patricia. I. I. Moreno, Diana Molinares, Tulay Koru-Sengul, Frank. J. J. Penedo
Summary: Cancer survivors often face physical inactivity, which is not effectively addressed. The My Wellness Check program provides a screening and referral system to monitor physical activity and connect survivors to cancer rehabilitation medicine. This study examined the assessment of physical activity and referrals to cancer rehabilitation medicine.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Hannah M. Cranford, Tulay Koru-Sengul, Gilberto Lopes, Paulo S. Pinheiro
Summary: This study found disparities in lung cancer incidence rates and tumor characteristics among Black and Hispanic populations in the United States. Understanding these differences is crucial for targeted public health measures and further research in never-smokers, especially among females and considering environmental factors.
Article
Multidisciplinary Sciences
Yiyun Zhao, Hui Lin, Hassan Elahi, Feng Miao, Saleem Riaz
Summary: This paper proposes a novel fault-tolerant control strategy for the clamping force sensor in the electromechanical brake system, aiming to enhance the system reliability. By analyzing the causes of clamping force sensor failure, the relationship between motor output torque and braking force, and considering the hysteresis characteristics of external clamping forces, a clamping force estimation method is presented. Combined with an enhanced extended state observer and power fast terminal sliding-mode control, the proposed strategy achieves dynamic response and improved anti-interference ability.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Meeting Abstract
Oncology
John Siemon, Sophia George, Deukwoo Kwon, Feng Miao, Angel Tabuyo-Martin, Molly Roy, David Samuel, Marilyn Huang, Joseph Pearson, Abdulrahman Sinno, Matthew Schlumbrecht
GYNECOLOGIC ONCOLOGY
(2022)
Letter
Dermatology
Michael S. Chang, Kevin J. Moore, Nicole Trepanowski, Tulay Koru-Sengul, Rebecca I. Hartman
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)