β-Adrenergic signaling blocks murine CD8+ T-cell metabolic reprogramming during activation: a mechanism for immunosuppression by adrenergic stress

Adrenergic nerves activate an angio-metabolic switch in prostate cancer

(2017) Ali H. Zahalka et al.   SCIENCE

Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses

(2017) Nikolaos Patsoukis et al.   Frontiers in Immunology

Sympathetic innervation, norepinephrine content, and norepinephrine turnover in orthotopic and spontaneous models of breast cancer

(2016) Mercedes J. Szpunar et al.   BRAIN BEHAVIOR AND IMMUNITY

β-Adrenergic-stimulated macrophages: Comprehensive localization in the M1-M2 spectrum

(2016) Donald M. Lamkin et al.   BRAIN BEHAVIOR AND IMMUNITY

Sympathetic neural signaling via the β2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8+ T-cell effector function

(2016) Leonardo D. Estrada et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

(2016) Nicole E. Scharping et al.   IMMUNITY

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion

(2016) Bertram Bengsch et al.   IMMUNITY

β-Adrenergic modulation of cancer cell proliferation: available evidence and clinical perspectives

(2016) Marisa Coelho et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions

(2016) Gaspard Cretenet et al.   Scientific Reports

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

T cell metabolism drives immunity

(2015) Michael D. Buck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Housing Temperature–Induced Stress Is Suppressing Murine Graft-versus-Host Disease through β2-Adrenergic Receptor Signaling

(2015) Nicholas D. Leigh et al.   JOURNAL OF IMMUNOLOGY

Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation

(2015) Jason W.-L. Eng et al.   Nature Communications

Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions

(2015) Clovis S. Palmer et al.   Frontiers in Immunology

A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic response

(2014) Jason W.-L. Eng et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways

(2014) S. R. Jacobs et al.   JOURNAL OF IMMUNOLOGY

Metabolic Regulation of T Lymphocytes

(2013) Nancie J. MacIver et al.   Annual Review of Immunology

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

(2013) Madhusudhanan Sukumar et al.   JOURNAL OF CLINICAL INVESTIGATION

Adrenergic Regulation of IgE Involves Modulation of CD23 and ADAM10 Expression on Exosomes

(2013) C. J. Padro et al.   JOURNAL OF IMMUNOLOGY

Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

(2013) K. M. Kokolus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fueling Immunity: Insights into Metabolism and Lymphocyte Function

(2013) E. L. Pearce et al.   SCIENCE

Metabolic pathways in T cell fate and function

(2012) Valerie A. Gerriets et al.   TRENDS IN IMMUNOLOGY

Epigenetic regulation of beta2-adrenergic receptor expression in TH1 and TH2 cells

(2010) Jaclyn W. McAlees et al.   BRAIN BEHAVIOR AND IMMUNITY

The metabolic life and times of a T-cell

(2010) Ryan D. Michalek et al.   IMMUNOLOGICAL REVIEWS

Anergic T Cells Are Metabolically Anergic

(2009) Y. Zheng et al.   JOURNAL OF IMMUNOLOGY

Sympathetic nervous system control of anti-influenza CD8+ T cell responses

(2009) K. M. Grebe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA